Characterization of a vaccinia virus-encoded double-stranded RNA-binding protein that may be involved in inhibition of the double-stranded RNA-dependent protein kinase.
about
Orthopoxvirus genes that mediate disease virulence and host tropismInfluenza A virus NS1 protein targets poly(A)-binding protein II of the cellular 3'-end processing machinery.The E3L gene of vaccinia virus encodes an inhibitor of the interferon-induced, double-stranded RNA-dependent protein kinaseA conserved double-stranded RNA-binding domainThe E3L and K3L vaccinia virus gene products stimulate translation through inhibition of the double-stranded RNA-dependent protein kinase by different mechanismsImpact of protein kinase PKR in cell biology: from antiviral to antiproliferative actionViral encounters with 2',5'-oligoadenylate synthetase and RNase L during the interferon antiviral responseRecombinant Ranaviruses for Studying Evolution of Host-Pathogen Interactions in Ectothermic VertebratesCoronavirus gene 7 counteracts host defenses and modulates virus virulenceActivation of stress response pathways promotes formation of antiviral granules and restricts virus replicationIn vitro activation of the interferon-induced, double-stranded RNA-dependent protein kinase PKR by RNA from the 3' untranslated regions of human alpha-tropomyosin.Inhibition of double-stranded RNA-dependent protein kinase PKR by vaccinia virus E3: role of complex formation and the E3 N-terminal domain.Both carboxy- and amino-terminal domains of the vaccinia virus interferon resistance gene, E3L, are required for pathogenesis in a mouse model.The vaccinia virus K3L gene product potentiates translation by inhibiting double-stranded-RNA-activated protein kinase and phosphorylation of the alpha subunit of eukaryotic initiation factor 2Translational control of viral gene expression in eukaryotesAntisense RNA: function and fate of duplex RNA in cells of higher eukaryotes.Blockade of interferon induction and action by the E3L double-stranded RNA binding proteins of vaccinia virus.Alphavirus minus-strand synthesis and persistence in mouse embryo fibroblasts derived from mice lacking RNase L and protein kinase R.Genetic screen of a mutant poxvirus library identifies an ankyrin repeat protein involved in blocking induction of avian type I interferon.Mutational analysis of vaccinia virus E3 protein: the biological functions do not correlate with its biochemical capacity to bind double-stranded RNAReversal of the interferon-sensitive phenotype of a vaccinia virus lacking E3L by expression of the reovirus S4 gene.Delay of vaccinia virus-induced apoptosis in nonpermissive Chinese hamster ovary cells by the cowpox virus CHOhr and adenovirus E1B 19K genes.Ectromelia virus RING finger protein is localized in virus factories and is required for virus replication in macrophagesRescue of vaccinia virus lacking the E3L gene by mutants of E3L.Mutational analysis of the vaccinia virus E3 protein defines amino acid residues involved in E3 binding to double-stranded RNA.Double-stranded RNA is a trigger for apoptosis in vaccinia virus-infected cells.PKR Transduces MDA5-Dependent Signals for Type I IFN Induction.Evasion of the Innate Immune Type I Interferon System by Monkeypox Virus.Loss of protein kinase PKR expression in human HeLa cells complements the vaccinia virus E3L deletion mutant phenotype by restoration of viral protein synthesisProducts of the porcine group C rotavirus NSP3 gene bind specifically to double-stranded RNA and inhibit activation of the interferon-induced protein kinase PKR.Degradation of the interferon-induced 68,000-M(r) protein kinase by poliovirus requires RNAProtein kinase PKR-dependent activation of mitogen-activated protein kinases occurs through mitochondrial adapter IPS-1 and is antagonized by vaccinia virus E3L.The attenuated NYCBH vaccinia virus deleted for the immune evasion gene, E3L, completely protects mice against heterologous challenge with ectromelia virus.Variola virus E3L Zα domain, but not its Z-DNA binding activity, is required for PKR inhibitionRNA-binding proteins that specifically recognize the selenocysteine insertion sequence of human cellular glutathione peroxidase mRNA.Ectromelia virus accumulates less double-stranded RNA compared to vaccinia virus in BS-C-1 cells.Double-stranded RNA binding by a heterodimeric complex of murine cytomegalovirus m142 and m143 proteins.Regulation of vaccinia virus E3 protein by small ubiquitin-like modifier proteins.Possible involvement of the double-stranded RNA-binding core protein sigmaA in the resistance of avian reovirus to interferon.Inhibition of the RNA polymerase III-mediated dsDNA-sensing pathway of innate immunity by vaccinia virus protein E3.
P2860
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P2860
Characterization of a vaccinia virus-encoded double-stranded RNA-binding protein that may be involved in inhibition of the double-stranded RNA-dependent protein kinase.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Characterization of a vaccinia ...... RNA-dependent protein kinase.
@en
type
label
Characterization of a vaccinia ...... RNA-dependent protein kinase.
@en
prefLabel
Characterization of a vaccinia ...... RNA-dependent protein kinase.
@en
P2093
P1433
P1476
Characterization of a vaccinia ...... RNA-dependent protein kinase.
@en
P2093
P304
P356
10.1016/0042-6822(91)90768-7
P407
P577
1991-11-01T00:00:00Z