Amino Acid Substitutions Associated with Avian H5N6 Influenza A Virus Adaptation to Mice

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Amino Acid Substitutions HA A150V, PA A343T, and PB2 E627K Increase the Virulence of H5N6 Influenza Virus in Mice.Patient-derived avian influenza A (H5N6) virus is highly pathogenic in mice but can be effectively treated by anti-influenza polyclonal antibodies.

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Amino Acid Substitutions Associated with Avian H5N6 Influenza A Virus Adaptation to Mice

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Amino Acid Substitutions Associated with Avian H5N6 Influenza A Virus Adaptation to Mice

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Amino Acid Substitutions Associated with Avian H5N6 Influenza A Virus Adaptation to Mice

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Amino Acid Substitutions Associated with Avian H5N6 Influenza A Virus Adaptation to Mice

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Amino Acid Substitutions Associated with Avian H5N6 Influenza A Virus Adaptation to Mice

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Chunmao Zhang

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Hongliang Chai

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Jiajie Zhang

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Jiaming Li

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Jun Qian

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Lina Liu

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Linna Liu

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Min Zhi

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Shaoxia Lu

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Xiaoyu Yang

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New world bats harbor diverse influenza A viruses

Epidemiology, Evolution, and Recent Outbreaks of Avian Influenza Virus in China

Hemagglutinin homologue from H17N10 bat influenza virus exhibits divergent receptor-binding and pH-dependent fusion activities

A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission

Avian flu: influenza virus receptors in the human airway

Airborne transmission of influenza A/H5N1 virus between ferrets

Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets

Human infection with a novel avian-origin influenza A (H7N9) virus

Human influenza virus A/HongKong/156/97 (H5N1) infection.

The PB2 E627K mutation contributes to the high polymerase activity and enhanced replication of H7N9 influenza virus.

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scholarly article

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10.3389/FMICB.2017.01763

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2017-09-15T00:00:00Z

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28966609

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5605651

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Amino Acid Substitutions Associated with Avian H5N6 Influenza A Virus Adaptation to Mice

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Amino Acid Substitutions Associated with Avian H5N6 Influenza A Virus Adaptation to Mice

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