The discovery of natalizumab, a potent therapeutic for multiple sclerosis.
about
No quiet surrender: molecular guardians in multiple sclerosis brainInhibition of G-protein βγ signaling enhances T cell receptor-stimulated interleukin 2 transcription in CD4+ T helper cellsAn interferon-β-resistant and NLRP3 inflammasome-independent subtype of EAE with neuronal damageGoing viral and the fatal vulnerability of neurons from immunity, not from infection.Role reversal: infiltrating T cells protect the brain.Early treatment with anti-VLA-4 mAb can prevent the infiltration and/or development of pathogenic CD11b+CD4+ T cells in the CNS during progressive EAE.Researchers Expand Focus on Progressive Forms Of Multiple Sclerosis: Efforts to Pinpoint the Beginning of Disease May Yield Clues to Treatment.Apigenin, a Natural Flavonoid, Attenuates EAE Severity Through the Modulation of Dendritic Cell and Other Immune Cell Functions.A Journey in Science: The Privilege of Exploring the Brain and the Immune System.Development of therapies for autoimmune disease at Stanford: a tale of multiple shots and one goal.A risk classification for immunosuppressive treatment-associated progressive multifocal leukoencephalopathy.Natalizumab for Multiple Sclerosis: A Case in Point for the Impact of Translational Neuroimmunology.Natalizumab in multiple sclerosis: discontinuation, progressive multifocal leukoencephalopathy and possible use in children.Adhesion Molecules: Master Controllers of the Circulatory System.Visualizing context-dependent calcium signaling in encephalitogenic T cells in vivo by two-photon microscopy.Beyond Clotting: A Role of Platelets in CNS Repair?Inflammatory cytokines at the summits of pathological signal cascades in brain diseases.A Tip leads cytotoxic T cells to the crime scene in neuroinflammation.Weighing in on autoimmune disease: 'Hub-and-spoke' T cell traffic in autoimmunity.Wnt/β-Catenin Signaling Induces Integrin α4β1 in T Cells and Promotes a Progressive Neuroinflammatory Disease in Mice.Piet Mondrian's trees and the evolution in understanding multiple sclerosis, Charcot Prize Lecture 2011.
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The discovery of natalizumab, a potent therapeutic for multiple sclerosis.
description
2012 nî lūn-bûn
@nan
2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
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2012年論文
@zh-tw
2012年论文
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2012年论文
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2012年论文
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name
The discovery of natalizumab, a potent therapeutic for multiple sclerosis.
@en
type
label
The discovery of natalizumab, a potent therapeutic for multiple sclerosis.
@en
prefLabel
The discovery of natalizumab, a potent therapeutic for multiple sclerosis.
@en
P2860
P356
P1476
The discovery of natalizumab, a potent therapeutic for multiple sclerosis.
@en
P2093
Lawrence Steinman
P2860
P304
P356
10.1083/JCB.201207175
P407
P577
2012-10-01T00:00:00Z