Intestinal immunopathology is associated with decreased CD73-generated adenosine during lethal infection. - Wikidata - wikimedia - TriplyDB

Intestinal immunopathology is associated with decreased CD73-generated adenosine during lethal infection.

Intestinal immunopathology is associated with decreased CD73-generated adenosine during lethal infection.

http://www.wikidata.org/entity/Q41666752

about

Fish gut-liver immunity during homeostasis or inflammation revealed by integrative transcriptome and proteome studies.Extracellular adenosine generation in the regulation of pro-inflammatory responses and pathogen colonization.The ectonucleotidases CD39 and CD73: Novel checkpoint inhibitor targets.Purinergic Signaling: A Common Path in the Macrophage Response against Mycobacterium tuberculosis and Toxoplasma gondii.Unconventional Pro-inflammatory CD4+ T Cell Response in B Cell-Deficient Mice Infected with Trypanosoma cruzi.Cutting Edge: Adenosine A2a Receptor Signals Inhibit Germinal Center T Follicular Helper Cell Differentiation during the Primary Response to Vaccination.Unfolding Role of a Danger Molecule Adenosine Signaling in Modulation of Microbial Infection and Host Cell Response.miR-130a and miR-212 Disrupt the Intestinal Epithelial Barrier through Modulation of PPARγ and Occludin Expression in Chronic Simian Immunodeficiency Virus-Infected Rhesus Macaques.CD39 is upregulated during activation of mouse and human T cells and attenuates the immune response to Listeria monocytogenes.

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Intestinal immunopathology is associated with decreased CD73-generated adenosine during lethal infection.

http://www.wikidata.org/entity/Q41666752

description

2014 nî lūn-bûn

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Mucosal Immunology

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G Oldenhove

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H Shehade

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P2860

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression.

Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid

Retinoic acid imprints gut-homing specificity on T cells

Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid

Molecular mechanisms of ATP secretion during immunogenic cell death

Dendritic cells tolerized with adenosine A₂AR agonist attenuate acute kidney injury

Adenosine A2A receptor activation reduces recurrence and mortality from Clostridium difficile infection in mice following vancomycin treatment.

CD73 is expressed by human regulatory T helper cells and suppresses proinflammatory cytokine production and Helicobacter felis-induced gastritis in mice.

Much ado about adenosine: adenosine synthesis and function in regulatory T cell biology.

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10.1038/MI.2014.108

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