A metabolically competent human cell line expressing five cDNAs encoding procarcinogen-activating enzymes: application to mutagenicity testing.
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P1343
Bacterial and human cell mutagenicity study of some C18H10 cyclopenta-fused polycyclic aromatic hydrocarbons associated with fossil fuels combustionPartial inhibition of estrogen-induced mammary carcinogenesis in rats by tamoxifen: balance between oxidant stress and estrogen responsivenessMutagens in human breast lipid and milk: the search for environmental agents that initiate breast cancer.Human cytochromes P450: evolution and cDNA-directed expression.By-products of a former phenol manufacturing site in a small lake adjacent to a Superfund site in the Aberjona watershed.Synergistic and Antagonistic Mutation Responses of Human MCL-5 Cells to Mixtures of Benzo[a]pyrene and 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]pyridine: Dose-Related Variation in the Joint Effects of Common Dietary CarcinogensHepatocyte cell lines: their use, scope and limitations in drug metabolism studies.In vitro approaches to develop weight of evidence (WoE) and mode of action (MoA) discussions with positive in vitro genotoxicity results.The clastogenicity of 4NQO is cell-type dependent and linked to cytotoxicity, length of exposure and p53 proficiency.Assessment of the genotoxic potential of indirect chemical mutagens in HepaRG cells by the comet and the cytokinesis-block micronucleus assays.The application of in vitro models of drug metabolism and toxicity in drug discovery and drug development.The role of mitotic recombination in carcinogenesis.Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins.Role of human cytochrome P-450s in risk assessment and susceptibility to environmentally based disease.Cell transformation and genotoxicity induced by bis(2, 3-dichloro-1-propyl) ether.Heterocyclic aromatic amines induce DNA strand breaks and cell transformation.Inhibition of tolbutamide 4-methylhydroxylation by a series of non-steroidal anti-inflammatory drugs in V79-NH cells expressing human cytochrome P4502C10.
P2860
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P2860
A metabolically competent human cell line expressing five cDNAs encoding procarcinogen-activating enzymes: application to mutagenicity testing.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
A metabolically competent huma ...... ation to mutagenicity testing.
@en
type
label
A metabolically competent huma ...... ation to mutagenicity testing.
@en
prefLabel
A metabolically competent huma ...... ation to mutagenicity testing.
@en
P2093
P356
P1476
A metabolically competent huma ...... ation to mutagenicity testing.
@en
P2093
Gelboin HV
Gonzalez FJ
Langenbach R
Steimel DT
P304
P356
10.1021/TX00023A013
P4510
P577
1991-09-01T00:00:00Z