The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways.
about
CAST, a novel CD3epsilon-binding protein transducing activation signal for interleukin-2 production in T cellsThe transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chainZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinityMechanism of activation for Zap-70 catalytic activityT cell receptor (TCR) interacting molecule (TRIM), a novel disulfide-linked dimer associated with the TCR-CD3-zeta complex, recruits intracellular signaling proteins to the plasma membraneAnalysis of the interaction of ZAP-70 and syk protein-tyrosine kinases with the T-cell antigen receptor by plasmon resonanceThe kinase, SH3, and SH2 domains of Lck play critical roles in T-cell activation after ZAP-70 membrane localizationPositive and negative regulation of T-cell activation through kinases and phosphatasesChimeric antigen receptor-modified T cells in chronic lymphoid leukemiaDual role of the tyrosine activation motif of the Ig-alpha protein during signal transduction via the B cell antigen receptorT cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemiaMissing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptorsBinding of ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteinsT cell activationComparison of human B cell antigen receptor complexes: membrane-expressed forms of immunoglobulin (Ig)M, IgD, and IgG are associated with structurally related heterodimersInduction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chainDifferent roles for the Fc epsilon RI gamma chain as a function of the receptor contextCAR models: next-generation CAR modifications for enhanced T-cell functionChimeric Antigen Receptors Modified T-Cells for Cancer TherapyChimeric Antigen Receptor- and TCR-Modified T Cells Enter Main Street and Wall StreetNovel drug targets for personalized precision medicine in relapsed/refractory diffuse large B-cell lymphoma: a comprehensive reviewStructure of the Chicken CD3 / Heterodimer and Its Assembly with the T Cell ReceptorCD19-Chimeric Antigen Receptor T Cells for Treatment of Chronic Lymphocytic Leukaemia and Acute Lymphoblastic LeukaemiaCAR therapy: the CD19 paradigmT cell engineering as therapy for cancer and HIV: our synthetic futureAre BiTEs the "missing link" in cancer therapy?Specific interaction of topoisomerase II beta and the CD3 epsilon chain of the T cell receptor complexInteractions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motifSignaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphataseTargeted disruption of the CD3 eta locus causes high lethality in mice: modulation of Oct-1 transcription on the opposite strandAssociation of CD247 (CD3ζ) gene polymorphisms with T1D and AITD in the population of northern SwedenSignal transduction by Fc gamma RIII (CD16) is mediated through the gamma chainAssociation of the high-affinity receptor for IgG (Fc gamma RI) with the gamma subunit of the IgE receptorPhosphorylated T cell receptor zeta-chain and ZAP70 tandem SH2 domains form a 1:3 complex in vitroChimeric antigen receptor T cells for sustained remissions in leukemiaThe adaptor protein SAP directly associates with CD3ζ chain and regulates T cell receptor signaling.Distinct T cell receptor signaling requirements for perforin- or FasL-mediated cytotoxicity.Biophysical mechanism of T-cell receptor triggering in a reconstituted systemConserved transmembrane tyrosine residues of the TCR beta chain are required for TCR expression and function in primary T cells and hybridomas.Zeta chain of the T-cell receptor interacts with nef of simian immunodeficiency virus and human immunodeficiency virus type 2
P2860
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P2860
The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
The cytoplasmic domain of the ...... signal transduction pathways.
@en
type
label
The cytoplasmic domain of the ...... signal transduction pathways.
@en
prefLabel
The cytoplasmic domain of the ...... signal transduction pathways.
@en
P1433
P1476
The cytoplasmic domain of the ...... signal transduction pathways.
@en
P2093
P304
P356
10.1016/0092-8674(91)90314-O
P407
P577
1991-03-01T00:00:00Z