Generation of cAMP-activated chloride currents by expression of CFTR.
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Identification of mutations in the putative ATP-binding domain of the adrenoleukodystrophy geneMechanisms of lipid malabsorption in Cystic Fibrosis: the impact of essential fatty acids deficiencyCorrection of chloride transport and mislocalization of CFTR protein by vardenafil in the gastrointestinal tract of cystic fibrosis miceAnion transport in heartRegulation of CFTR chloride channels by syntaxin and Munc18 isoformsPathophysiology of gene-targeted mouse models for cystic fibrosisPhenanthrolines--a new class of CFTR chloride channel openersSubcellular localization of CFTR to endosomes in a ductal epitheliumExpression and regulation of the cystic fibrosis gene during rat liver regenerationLung infections associated with cystic fibrosis.Cystic fibrosis transmembrane conductance regulator facilitates ATP release by stimulating a separate ATP release channel for autocrine control of cell volume regulation.Perturbation of the pore of the cystic fibrosis transmembrane conductance regulator (CFTR) inhibits its atpase activity.Mechanisms of chloride transport in thymic lymphocytes.Abnormal secretagogue-induced intracellular free Ca2+ regulation in cystic fibrosis nasal epithelial cellsNine cystic fibrosis patients homozygous for the CFTR nonsense mutation R1162X have mild or moderate lung disease.CFTR transcripts are undetectable in lymphocytes and respiratory epithelial cells of a CF patient homozygous for the nonsense mutation R553X.Cystic fibrosis: exploiting its genetic basis in the hunt for new therapiesStructure and function of the cystic fibrosis transmembrane conductance regulator.Evolutionary analyses of ABC transporters of Dictyostelium discoideum.Nonsense mutation R1162X of the cystic fibrosis transmembrane conductance regulator gene does not reduce messenger RNA expression in nasal epithelial tissue.DeltaF508 CFTR processing correction and activity in polarized airway and non-airway cell monolayers.Regulation of CFTR expression and function during differentiation of intestinal epithelial cells.Cystic fibrosis transmembrane conductance regulator (CFTR) potentiator VX-770 (ivacaftor) opens the defective channel gate of mutant CFTR in a phosphorylation-dependent but ATP-independent manner.Structural and functional similarities between the nucleotide-binding domains of CFTR and GTP-binding proteinsConformation, independent of charge, in the R domain affects cystic fibrosis transmembrane conductance regulator channel openingsIdentification and regulation of the cystic fibrosis transmembrane conductance regulator-generated chloride channelSevere deficiency of cystic fibrosis transmembrane conductance regulator messenger RNA carrying nonsense mutations R553X and W1316X in respiratory epithelial cells of patients with cystic fibrosis.A microRNA network regulates expression and biosynthesis of wild-type and DeltaF508 mutant cystic fibrosis transmembrane conductance regulator.Proteomic identification of calumenin as a G551D-CFTR associated protein.Reversal of cystic fibrosis phenotype in a cultured Delta508 cystic fibrosis transmembrane conductance regulator cell line by oligonucleotide insertion.Effects of cystic fibrosis and congenital bilateral absence of the vas deferens-associated mutations on cystic fibrosis transmembrane conductance regulator-mediated regulation of separate channelsNa(+)-dependent transporters mediate HCO(3)(-) salvage across the luminal membrane of the main pancreatic duct.The dual phosphodiesterase 3 and 4 inhibitor RPL554 stimulates CFTR and ciliary beating in primary cultures of bronchial epithelia.Molecular analysis of the ovine cystic fibrosis transmembrane conductance regulator gene.Transfer of a constitutive viral promoter-cystic fibrosis transmembrane conductance regulator cDNA to human epithelial cells conveys resistance to down-regulation of cAMP-regulated Cl- secretion in the presence of inflammatory stimuli.Identification of an ion channel-forming motif in the primary structure of CFTR, the cystic fibrosis chloride channelExpression of the human cystic fibrosis transmembrane conductance regulator gene in the mouse lung after in vivo intratracheal plasmid-mediated gene transfer.Characteristic multiorgan pathology of cystic fibrosis in a long-living cystic fibrosis transmembrane regulator knockout murine model.Genetic determination of exocrine pancreatic function in cystic fibrosisIdentification of a nonframeshift 84-bp deletion in exon 13 of the cystic fibrosis gene.
P2860
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P2860
Generation of cAMP-activated chloride currents by expression of CFTR.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Generation of cAMP-activated chloride currents by expression of CFTR.
@en
type
label
Generation of cAMP-activated chloride currents by expression of CFTR.
@en
prefLabel
Generation of cAMP-activated chloride currents by expression of CFTR.
@en
P2093
P356
P1433
P1476
Generation of cAMP-activated chloride currents by expression of CFTR.
@en
P2093
P304
P356
10.1126/SCIENCE.1704151
P407
P577
1991-02-01T00:00:00Z