Differences between natural and recombinant G protein-coupled receptor systems with varying receptor/G protein stoichiometry.
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Human gamma-aminobutyric acid type B receptors are differentially expressed and regulate inwardly rectifying K+ channelsThe human 5-HT7 serotonin receptor splice variants: constitutive activity and inverse agonist effectsHeterotrimeric G proteins precouple with G protein-coupled receptors in living cells.Differential activation of dual signaling responses by human H1 and H2 histamine receptorsActivity of adenosine diphosphates and triphosphates on a P2Y(T) -type receptor in brain capillary endothelial cellsBrain alpha(2)-adrenoceptors in monoamine-depleted rats: increased receptor density, G coupling proteins, receptor turnover and receptor mRNAEvidence for a tandem two-site model of ligand binding to muscarinic acetylcholine receptorsCocaine withdrawal enhances long-term potentiation induced by corticotropin-releasing factor at central amygdala glutamatergic synapses via CRF, NMDA receptors and PKABoth ligand- and cell-specific parameters control ligand agonism in a kinetic model of g protein-coupled receptor signaling.Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.The muscarinic M(5) receptor: a silent or emerging subtype?(8-Naphthalen-1-ylmethyl-4-oxo-1-phenyl-1,3,8-triaza-spiro[4. 5]dec-3-yl)-acetic acid methyl ester (NNC 63-0532) is a novel potent nociceptin receptor agonist.Identification of G protein-coupled receptors for Drosophila PRXamide peptides, CCAP, corazonin, and AKH supports a theory of ligand-receptor coevolution.Effects of clozapine and 2,5-dimethoxy-4-methylamphetamine [DOM] on 5-HT2A receptor expression in discrete brain areas.The P2Y(1) receptor closes the N-type Ca(2+) channel in neurones, with both adenosine triphosphates and diphosphates as potent agonists.Efficacy in CB1 receptor-mediated signal transductionThe design, synthesis and pharmacological characterization of novel β₂-adrenoceptor antagonists.GPR142 Agonists Stimulate Glucose-Dependent Insulin Secretion via Gq-Dependent SignalingTargeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases.Methanocarba analogues of purine nucleosides as potent and selective adenosine receptor agonists.Extracellular loop II modulates GTP sensitivity of the prostaglandin EP3 receptorMolecular mechanisms that control initiation and termination of physiological depolarization-evoked transmitter release.Cellular mechanisms of nociceptin/orphanin FQ (N/OFQ) peptide (NOP) receptor regulation and heterologous regulation by N/OFQ.A1 adenosine receptor attenuates intracerebral hemorrhage-induced secondary brain injury in rats by activating the P38-MAPKAP2-Hsp27 pathway.Agonist high- and low-affinity states of dopamine D₂ receptors: methods of detection and clinical implications.A perspective on more effective GPCR-targeted drug discovery efforts.ET-1 induced Elevation of intracellular calcium in clonal neuronal and embryonic kidney cells involves endogenous endothelin-A receptors linked to phospholipase C through Gα(q/11)Co-expression of mu and delta opioid receptors as receptor-G protein fusions enhances both mu and delta signalling via distinct mechanisms.Expression, binding, and signaling properties of CRF2(a) receptors endogenously expressed in human retinoblastoma Y79 cells: passage-dependent regulation of functional receptors.The human serotonin 1A receptor expressed in neuronal cells: toward a native environment for neuronal receptors.Free fatty acid receptor 1 (FFA(1)R/GPR40) and its involvement in fatty-acid-stimulated insulin secretion.Rate limiting factors in melanocortin 1 receptor signalling through the cAMP pathway.Regulation of the avidity of ternary complexes containing the human 5-HT(1A) receptor by mutation of a receptor contact site on the interacting G protein alpha subunit.Processing of GABABR1 in heterologous expression systems.High constitutive activity of the human formyl peptide receptor.G protein stoichiometry dictates biased agonism through distinct receptor-G protein partitioning.CysLT1 receptor-induced human airway smooth muscle cells proliferation requires ROS generation, EGF receptor transactivation and ERK1/2 phosphorylation.Selective stabilization of the high affinity binding conformation of glucagon receptor by the long splice variant of Galpha(s).Dual coupling of opioid receptor-like (ORL1) receptors to adenylyl cyclase in the different layers of the rat main olfactory bulb.Agonists of the P2Y(AC)-receptor activate MAP kinase by a ras-independent pathway in rat C6 glioma.
P2860
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P2860
Differences between natural and recombinant G protein-coupled receptor systems with varying receptor/G protein stoichiometry.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Differences between natural an ...... eptor/G protein stoichiometry.
@en
type
label
Differences between natural an ...... eptor/G protein stoichiometry.
@en
prefLabel
Differences between natural an ...... eptor/G protein stoichiometry.
@en
P1476
Differences between natural an ...... eptor/G protein stoichiometry.
@en
P2093
P304
P356
10.1016/S0165-6147(97)01136-X
P577
1997-12-01T00:00:00Z