about
Peroxisome protein import: a complex journeyExploration of the HIF-1α/p300 interface using peptide and Adhiron phage display technologiesHigh-content, high-throughput screening for the identification of cytotoxic compounds based on cell morphology and cell proliferation markersChemical generation and modification of peptides containing multiple dehydroalaninesThe parallel synthesis of a disaccharide library using a solid phase, peptide-templated strategy.PEX14 binding to Arabidopsis PEX5 has differential effects on PTS1 and PTS2 cargo occupancy of the receptorA small molecule with differential effects on the PTS1 and PTS2 peroxisome matrix import pathways.Solid-phase methodology for synthesis of O-alkylated aromatic oligoamide inhibitors of α-helix-mediated protein-protein interactionsAn inhibitor of oil body mobilization in Arabidopsis.Small-molecule proteomimetic inhibitors of the HIF-1α-p300 protein-protein interaction.Probing Protein Surfaces: QSAR Analysis with Helix Mimetics.Synthesis of highly functionalized oligobenzamide proteomimetic foldamers by late stage introduction of sensitive groups.Covalent Label Transfer between Peroxisomal Importomer Components Reveals Export-driven Import InteractionsTowards "bionic" proteins: replacement of continuous sequences from HIF-1α with proteomimetics to create functional p300 binding HIF-1α mimics.Getting a camel through the eye of a needle: the import of folded proteins by peroxisomes.Peroxisome biogenesis and positioning.Correction: Peroxisome protein import: a complex journey.Trivalent Gd-DOTA reagents for modification of proteins.Trafficking modulator TENin1 inhibits endocytosis, causes endomembrane protein accumulation at the pre-vacuolar compartment and impairs gravitropic response in Arabidopsis thaliana.An efficient method for synthesising unsymmetrical silaketals: substrates for ring-closing, including macrocycle-closing, metathesis.Design, synthesis and in vitro evaluation of novel bivalent S-adenosylmethionine analogues.Modular Synthesis of Diverse Natural Product-Like Macrocycles: Discovery of Hits with Antimycobacterial Activity.A protein-based pentavalent inhibitor of the cholera toxin B-subunit.Economical and scalable synthesis of 6-amino-2-cyanobenzothiazole.Towards designer organelles by subverting the peroxisomal import pathwayExperimental validation of plant peroxisomal targeting prediction algorithms by systematic comparison of in vivo import efficiency and in vitro PTS1 binding affinity.A fluorous-tagged "safety catch" linker for preparing heterocycles by ring-closing metathesis.Improved syntheses of high hole mobility phthalocyanines: A case of steric assistance in the cyclo-oligomerisation of phthalonitriles.Optimizing protein stability in vivoA fluorous-tagged linker from which small molecules are released by ring-closing metathesisSynthesis of natural-product-like molecules with over eighty distinct scaffoldsOligobenzamide proteomimetic inhibitors of the p53-hDM2 protein-protein interaction.Phosphorylation as a tool to modulate aggregation propensity and to predict fibril architecture.Synthesis of skeletally diverse alkaloid-like molecules: exploitation of metathesis substrates assembled from triplets of building blocksHydrocarbon constrained peptides - understanding preorganisation and binding affinity.Double quick, double click reversible peptide "stapling".Activity-Directed Synthesis with Intermolecular Reactions: Development of a Fragment into a Range of Androgen Receptor Agonists.Ion Mobility Spectrometry-Mass Spectrometry of Intrinsically Unfolded Proteins: Trying to Put Order into Disorder.Synthesis of functionalised aromatic oligamide rods.Identification of stable S-adenosylmethionine (SAM) analogues derivatised with bioorthogonal tags: effect of ligands on the affinity of the E. coli methionine repressor, MetJ, for its operator DNA.
P50
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P50
description
hulumtues
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Stuart L Warriner
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Stuart L Warriner
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Stuart L Warriner
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Stuart L. Warriner
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Stuart L. Warriner
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Stuart L Warriner
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Stuart Laurence Warriner
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Stuart Laurence Warriner
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Stuart Laurence Warriner
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Stuart L Warriner
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Stuart L Warriner
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Stuart L Warriner
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Stuart L. Warriner
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P185
P214
P268
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P6366
P106
P1153
6603607591
P1416
P2031
1996-01-01T00:00:00Z
P21
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0000 0000 6313 8817
P214
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P31
P4012
P496
0000-0002-7589-6011