Stable expression of the human TSH receptor in CHO cells and characterization of differentially expressing clones.
about
P1343
Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors.Pharmacological characterization of the human P2Y11 receptorRole of complex asparagine-linked oligosaccharides in the expression of a functional thyrotropin receptorLimitations of the semisynthetic library approach for obtaining human monoclonal autoantibodies to the thyrotropin receptor of Graves' disease.Cloning and functional expression of the canine anaphylatoxin C5a receptor. Evidence for high interspecies variability.Concentration-dependent regulation of thyrotropin receptor function by thyroid-stimulating antibody.Thyrotropin isoforms: implications for thyrotropin analysis and clinical practice.Distinct roles of deiodinases on the phenotype of Mct8 defect: a comparison of eight different mouse genotypes.Tissue-specific posttranslational modification allows functional targeting of thyrotropinThe selective loss of the type 2 iodothyronine deiodinase in mouse thyrotrophs increases basal TSH but blunts the thyrotropin response to hypothyroidism.TNFalpha mediates the skeletal effects of thyroid-stimulating hormoneThyroid-specific inactivation of KIF3A alters the TSH signaling pathway and leads to hypothyroidism.Interaction of chemokine receptor CCR5 with its ligands: multiple domains for HIV-1 gp120 binding and a single domain for chemokine bindingDisruption of the melanin-concentrating hormone receptor 1 (MCH1R) affects thyroid function.Molecular cloning, functional expression and pharmacological characterization of a mouse melanocortin receptor geneClinical review: Clinical utility of TSH receptor antibodies.Genetic immunization of outbred mice with thyrotropin receptor cDNA provides a model of Graves' disease.The vitamin d receptor in thyroid development and function.American Thyroid Association Guide to investigating thyroid hormone economy and action in rodent and cell models.Overexpression of Interleukin-4 in the Thyroid of Transgenic Mice Upregulates the Expression of Duox1 and the Anion Transporter Pendrin.The second extracellular loop of CCR5 is the major determinant of ligand specificity.A luminescent bioassay for thyroid blocking antibodies.Engineering the human thyrotropin receptor ectodomain from a non-secreted form to a secreted, highly immunoreactive glycoprotein that neutralizes autoantibodies in Graves' patients' sera.Detection of thyroid stimulating (TSAB)- and thyrotropin stimulation blocking (TSBAB) antibodies with CHO cell lines expressing different TSH-receptor numbers.Production of bioactive amino-terminal domain of the thyrotropin receptor via insertion in the plasma membrane by a glycosylphosphatidylinositol anchor.The orphan receptor cDNA RDC7 encodes an A1 adenosine receptor.Transfection with the cDNA of the human thyrotropin receptor of a poorly differentiated rat thyroid cell line (FRT).Shedding of human thyrotropin receptor ectodomain. Involvement of a matrix metalloprotease.Measurement of TSH receptor blocking immunoglobulins using 3H-adenine incorporation into FRTL-5 and JPO9 cells: use in a child with neonatal hypothyroidism.Detection of antibodies blocking thyrotropin effect using Chinese hamster ovary cells transfected with the cloned human TSH receptor.Measurement of thyroid stimulating immunoglobulins in a new cell line transfected with a functional human TSH receptor (JPO9 cells), compared with an assay using FRTL-5 cells.Role of caveolin-1 in thyroid phenotype, cell homeostasis, and hormone synthesis: in vivo study of caveolin-1 knockout mice.Gene transfer effects on various cationic amphiphiles in CHO cells.Measurement of cAMP accumulation in Chinese hamster ovary cells transfected with the recombinant human TSH receptor (CHO-R): a new bioassay for human thyrotropin.In vitro assay of thyroid disruptors affecting TSH-stimulated adenylate cyclase activity.Induction of hyperthyroidism in mice by intradermal immunization with DNA encoding the thyrotropin receptor.Induction of thyroiditis in mice with thyrotropin receptor lacking serologically dominant regions.Characterisation of the antibody response to the extracellular region of recombinant thyrotropin receptor.Dominant role of thyrotropin-releasing hormone in the hypothalamic-pituitary-thyroid axis.
P2860
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P2860
Stable expression of the human TSH receptor in CHO cells and characterization of differentially expressing clones.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Stable expression of the human ...... ferentially expressing clones.
@en
type
label
Stable expression of the human ...... ferentially expressing clones.
@en
prefLabel
Stable expression of the human ...... ferentially expressing clones.
@en
P2093
P1476
Stable expression of the human ...... ferentially expressing clones.
@en
P2093
J E Dumont
M Parmentier
P304
P356
10.1016/0006-291X(90)90789-P
P577
1990-09-01T00:00:00Z