Huntingtin N17 domain is a reactive oxygen species sensor regulating huntingtin phosphorylation and localization.
about
Is Huntingtin Dispensable in the Adult Brain?Post-Translational Modifications (PTMs), Identified on Endogenous Huntingtin, Cluster within Proteolytic Domains between HEAT Repeats.Proteins Containing Expanded Polyglutamine Tracts and Neurodegenerative Disease.Huntingtin is a scaffolding protein in the ATM oxidative DNA damage response complex.Post-translational modifications clustering within proteolytic domains decrease mutant huntingtin toxicity.The central role of DNA damage and repair in CAG repeat diseases.Proteostasis in Huntington's disease: disease mechanisms and therapeutic opportunities.Transcriptional Dysregulation and Post-translational Modifications in Polyglutamine Diseases: From Pathogenesis to Potential Therapeutic Strategies.
P2860
Q30353134-35EF449C-97F7-44A4-9A9B-AA8502D4F1D2Q38374920-2E1AAEC1-67BB-4DCE-9DD5-9F5C2BFC72B4Q39124557-5FC98339-32C4-459B-BAE6-E025233F44B2Q45299796-5DF598F9-DA95-4D27-A4CB-E2176C5CCB14Q45304677-BBE24BF6-D430-4E38-A5BE-60AD3D4837D4Q50118950-8544FD0B-B69B-4FF1-94AC-9D9EB3E634DFQ52605399-CCC7E940-2CD6-438A-8D30-B42C4E291FAFQ54965657-015CFF98-1693-430E-8175-B23EAAED14E2
P2860
Huntingtin N17 domain is a reactive oxygen species sensor regulating huntingtin phosphorylation and localization.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Huntingtin N17 domain is a rea ...... sphorylation and localization.
@en
type
label
Huntingtin N17 domain is a rea ...... sphorylation and localization.
@en
prefLabel
Huntingtin N17 domain is a rea ...... sphorylation and localization.
@en
P2093
P2860
P356
P1476
Huntingtin N17 domain is a rea ...... sphorylation and localization.
@en
P2093
Andrew J Mocle
Jianrun Xia
Laura F DiGiovanni
Ray Truant
P2860
P304
P356
10.1093/HMG/DDW234
P577
2016-07-27T00:00:00Z