Predicting functions from protein sequences--where are the bottlenecks?
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Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidaseComplex transcriptional effects of p63 isoforms: identification of novel activation and repression domainsMicrobial relatives of the seed storage proteins of higher plants: conservation of structure and diversification of function during evolution of the cupin superfamilyThe what, where, how and why of gene ontology--a primer for bioinformaticiansSplitting p63Towards understanding the first genome sequence of a crenarchaeon by genome annotation using clusters of orthologous groups of proteins (COGs)Applying Support Vector Machines for Gene Ontology based gene function predictionGeneFarm, structural and functional annotation of Arabidopsis gene and protein families by a network of expertsELISA: structure-function inferences based on statistically significant and evolutionarily inspired observationsFIGENIX: intelligent automation of genomic annotation: expertise integration in a new software platformProtein molecular function prediction by Bayesian phylogenomics.Probabilistic annotation of protein sequences based on functional classifications.Using biological networks to improve our understanding of infectious diseasesSolution structure of the receptor tyrosine kinase EphB2 SAM domain and identification of two distinct homotypic interaction sitesFunctional implications from crystal structures of the conserved Bacillus subtilis protein Maf with and without dUTPInferred Biomolecular Interaction Server--a web server to analyze and predict protein interacting partners and binding sitesTracking the Evolution of Polymerase Genes of Influenza A Viruses during Interspecies Transmission between Avian and Swine HostsPredicting functions of proteins in mouse based on weighted protein-protein interaction network and protein hybrid propertiesIdentification and tissue distribution of novel KET/p63 splice variantsExploring inconsistencies in genome-wide protein function annotations: a machine learning approachPAS domains: internal sensors of oxygen, redox potential, and lightQuantitative assessment of protein function prediction from metagenomics shotgun sequencesExploring the "dark matter" of a mammalian proteome by protein structure and function modeling.Enhancing HMM-based protein profile-profile alignment with structural features and evolutionary coupling informationQuantification of protein group coherence and pathway assignment using functional association.Combining heterogeneous data sources for accurate functional annotation of proteins.A likelihood ratio test for evolutionary rate shifts and functional divergence among proteins.Who's your neighbor? New computational approaches for functional genomics.RNRdb, a curated database of the universal enzyme family ribonucleotide reductase, reveals a high level of misannotation in sequences deposited to Genbank.Quality assessment of protein model-structures based on structural and functional similarities.Toprim--a conserved catalytic domain in type IA and II topoisomerases, DnaG-type primases, OLD family nucleases and RecR proteins.High precision multi-genome scale reannotation of enzyme function by EFICAz.The relationship between protein sequences and their gene ontology functions.FlowerPower: clustering proteins into domain architecture classes for phylogenomic inference of protein function.CORRIE: enzyme sequence annotation with confidence estimates.Quantitative assessment of relationship between sequence similarity and function similarity.A survey of orphan enzyme activitiesQuantitative sequence-function relationships in proteins based on gene ontology.HangOut: generating clean PSI-BLAST profiles for domains with long insertionsMore than 1,001 problems with protein domain databases: transmembrane regions, signal peptides and the issue of sequence homology.
P2860
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P2860
Predicting functions from protein sequences--where are the bottlenecks?
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Predicting functions from protein sequences--where are the bottlenecks?
@en
type
label
Predicting functions from protein sequences--where are the bottlenecks?
@en
prefLabel
Predicting functions from protein sequences--where are the bottlenecks?
@en
P2860
P356
P1433
P1476
Predicting functions from protein sequences--where are the bottlenecks?
@en
P2860
P2888
P304
P356
10.1038/NG0498-313
P407
P577
1998-04-01T00:00:00Z
P5875
P6179
1021131638