The glycosylation of the variant surface glycoproteins and procyclic acidic repetitive proteins of Trypanosoma brucei.
about
N-glycosylation enables high lateral mobility of GPI-anchored proteins at a molecular crowding thresholdInsight into a conserved lifestyle: protein-carbohydrate adhesion strategies of vector-borne pathogens.Cyclosporin A treatment of Leishmania donovani reveals stage-specific functions of cyclophilins in parasite proliferation and viabilityProtozoacidal Trojan-Horse: use of a ligand-lytic peptide for selective destruction of symbiotic protozoa within termite gutsEfficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies. African trypanosomes as paradigm.The suppression of galactose metabolism in procylic form Trypanosoma brucei causes cessation of cell growth and alters procyclin glycoprotein structure and copy number.Deletion of the TbALG3 gene demonstrates site-specific N-glycosylation and N-glycan processing in Trypanosoma brucei.Computer-aided identification of Trypanosoma brucei uridine diphosphate galactose 4'-epimerase inhibitors: toward the development of novel therapies for African sleeping sickness.Sequence requirements for trafficking of the CRAM transmembrane protein to the flagellar pocket of African trypanosomes.Secretory pathway of trypanosomatid parasites.Galactose metabolism is essential for the African sleeping sickness parasite Trypanosoma bruceiModeling of the N-glycosylated transferrin receptor suggests how transferrin binding can occur within the surface coat of Trypanosoma brucei.GPI-anchored proteins and free GPI glycolipids of procyclic form Trypanosoma brucei are nonessential for growth, are required for colonization of the tsetse fly, and are not the only components of the surface coat.Galactose starvation in a bloodstream form Trypanosoma brucei UDP-glucose 4'-epimerase conditional null mutant.GPI transamidase of Trypanosoma brucei has two previously uncharacterized (trypanosomatid transamidase 1 and 2) and three common subunitsThe molecular dynamics of Trypanosoma brucei UDP-galactose 4'-epimerase: a drug target for African sleeping sicknessThe de novo and salvage pathways of GDP-mannose biosynthesis are both sufficient for the growth of bloodstream-form Trypanosoma brucei.Surface sialic acids taken from the host allow trypanosome survival in tsetse fly vectors.Inhibition of nucleotide sugar transport in Trypanosoma brucei alters surface glycosylation.A Gene of the β3-Glycosyltransferase Family Encodes N-Acetylglucosaminyltransferase II Function in Trypanosoma bruceiDistinct donor and acceptor specificities of Trypanosoma brucei oligosaccharyltransferases.Identification and functional characterization of a highly divergent N-acetylglucosaminyltransferase I (TbGnTI) in Trypanosoma brucei.Life and times: synthesis, trafficking, and evolution of VSG.A conserved flagellar pocket exposed high mannose moiety is used by African trypanosomes as a host cytokine binding molecule.Identification of potential protein partners that bind to the variant surface glycoprotein in Trypanosoma equiperdum.TbGT8 is a bifunctional glycosyltransferase that elaborates N-linked glycans on a protein phosphatase AcP115 and a GPI-anchor modifying glycan in Trypanosoma brucei.Identification of a glycosylphosphatidylinositol anchor-modifying β1-3 galactosyltransferase in Trypanosoma bruceiTelomere components as potential therapeutic targets for treating microbial pathogen infections.Phosphoglucomutase is absent in Trypanosoma brucei and redundantly substituted by phosphomannomutase and phospho-N-acetylglucosamine mutase.Inhibitors incorporating zinc-binding groups target the GlcNAc-PI de-N-acetylase in Trypanosoma brucei, the causative agent of African sleeping sickness.Trypanosoma brucei UDP-glucose:glycoprotein glucosyltransferase has unusual substrate specificity and protects the parasite from stress.Trypanosoma brucei UDP-galactose-4'-epimerase in ternary complex with NAD+ and the substrate analogue UDP-4-deoxy-4-fluoro-alpha-D-galactose.Characterization, localization, essentiality, and high-resolution crystal structure of glucosamine 6-phosphate N-acetyltransferase from Trypanosoma brucei.Glycotyping of Trypanosoma brucei variant surface glycoprotein MITat1.8.GDP-mannose pyrophosphorylase is essential in the bloodstream form of Trypanosoma brucei.Trypanosoma brucei glycoproteins contain novel giant poly-N-acetyllactosamine carbohydrate chains.The glycan core of GPI-anchored proteins modulates aerolysin binding but is not sufficient: the polypeptide moiety is required for the toxin-receptor interaction.The N-acetyl-D-glucosaminylphosphatidylinositol De-N-acetylase of glycosylphosphatidylinositol biosynthesis is a zinc metalloenzyme.Removal or maintenance of inositol-linked acyl chain in glycosylphosphatidylinositol is critical in trypanosome life cycle.Characterization of a novel alanine-rich protein located in surface microdomains in Trypanosoma brucei.
P2860
Q27325470-0952B1B1-A8D8-4DE9-9B32-72A1E6C0E84EQ27472742-F5B59043-F916-45B6-87BB-6CF27D93F12FQ28474744-F193209F-EEB3-436D-AA7B-E4FCB4A01A2DQ28542848-902681D2-48DB-4BC1-A0C5-5EE32844F890Q31007389-A3CF25B9-1C8C-4D4F-8842-759E82BAB952Q31153696-F4C5E84B-EC70-4F5D-A0D8-569579AABA70Q33319071-F3A73EE7-18F3-4F41-98B2-EE3418A0530CQ33954211-1DD50B50-D6DF-4AD4-8F48-A1E6D1E46F25Q33964614-F58D271D-7406-43EC-A8F4-D277B10A6BC2Q33969495-438BD734-409A-40A4-9B0A-8E45BE14667DQ34027098-6DC46883-727A-47DC-B119-4DE6032832E8Q34229614-1366347C-197E-4C98-A97F-209B13D6155DQ35191010-A15041F4-37B7-4769-9CAE-E85DB85EA1A3Q35216711-698A3277-3189-446F-BAF0-460AB679EBFDQ35977478-E4F9B988-7B5C-4F7C-978B-D618B5E272D9Q36103511-062ACEDE-2247-4274-8764-C299CB127AD6Q36141595-5A19D473-F98D-42CF-BD56-38023E9D15BBQ36399214-A9843F40-5304-4B48-89DD-23CE863A910EQ36760357-1C3651EE-FEC5-4A27-A035-3A2EE40ABA45Q37034455-B65C7FEA-450B-4874-8FB2-15644849B82BQ37293056-B369BC5C-7FF0-43FE-8AB5-054F7B3B28B8Q37691619-DFF91B44-E10A-4EF7-8592-CF12DCAAE139Q38204562-1FFEB451-D9A4-459C-BBB6-04AF2E4415C7Q38299851-EB05F177-4E55-420E-BF47-74651E25FBE4Q38932866-DF92F313-1755-41CF-AA09-83F1F485A139Q39031763-1390B69A-AFCA-456A-9147-401C50C3050EQ39097406-D2E683E0-78DD-4203-A73E-DC3112923430Q41596462-BE7662B8-1365-411F-B226-CC0D5F7676CDQ41908027-53E73686-B106-4806-93DC-D361550EA173Q42135590-8B6D0DAB-69B8-463F-80C5-482D055631BDQ42182630-3A0CFEC3-52E3-4FAB-841D-A9AFC50F0D71Q42259106-EA4F2276-67ED-46E9-92BC-1C9446D2A530Q42263917-03295BF3-EB9E-4A27-AFE4-DF777BDD8CA3Q42429600-81149524-6A1F-4217-894A-AC15050B4E9DQ43240478-59C2A1CB-DCCA-47F5-809C-D01D8B06E939Q45127790-42A5E3C2-B916-4A79-9182-FB14D83188C3Q45711489-E840550F-4FA6-4549-866F-3E6E712E43A3Q46427537-DC82AFA6-16A5-4B78-9204-BA40DC7E540AQ46970703-A73E11A9-B329-4DAE-BDDA-79F9249A0638Q47887087-3F2E92CE-AFFB-43C1-A023-7474B4C9B806
P2860
The glycosylation of the variant surface glycoproteins and procyclic acidic repetitive proteins of Trypanosoma brucei.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
The glycosylation of the varia ...... roteins of Trypanosoma brucei.
@en
type
label
The glycosylation of the varia ...... roteins of Trypanosoma brucei.
@en
prefLabel
The glycosylation of the varia ...... roteins of Trypanosoma brucei.
@en
P2093
P1476
The glycosylation of the varia ...... proteins of Trypanosoma brucei
@en
P2093
P304
P356
10.1016/S0166-6851(97)00187-4
P577
1998-03-01T00:00:00Z