Crystal structure of the E230Q mutant of cAMP-dependent protein kinase reveals an unexpected apoenzyme conformation and an extended N-terminal A helix.
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Dynamics connect substrate recognition to catalysis in protein kinase ARealizing the Allosteric Potential of the Tetrameric Protein Kinase A RIα HoloenzymeA Conserved Non-canonical Motif in the Pseudoactive Site of the ROP5 Pseudokinase Domain Mediates Its Effect on Toxoplasma VirulenceMutants of protein kinase A that mimic the ATP-binding site of Aurora kinaseA Conserved Glu–Arg Salt Bridge Connects Coevolved Motifs That Define the Eukaryotic Protein Kinase FoldPhosphoryl Transfer by Protein Kinase A Is Captured in a Crystal LatticeRole of N-Terminal Myristylation in the Structure and Regulation of cAMP-Dependent Protein KinaseQuantitative assessment of protein structural models by comparison of H/D exchange MS data with exchange behavior accurately predicted by DXCOREX.Co-conserved features associated with cis regulation of ErbB tyrosine kinases.Dynamic architecture of a protein kinase.Structural and evolutionary adaptation of rhoptry kinases and pseudokinases, a family of coccidian virulence factorsCotranslational cis-phosphorylation of the COOH-terminal tail is a key priming step in the maturation of cAMP-dependent protein kinaseA helix scaffold for the assembly of active protein kinasesInfluence of N-myristylation and ligand binding on the flexibility of the catalytic subunit of protein kinase A.Structural and functional determinants of protein kinase CK2α: facts and open questions.An enriched structural kinase database to enable kinome-wide structure-based analyses and drug discoveryCalculating pKa values in the cAMP-dependent protein kinase: the effect of conformational change and ligand binding.Analysis of protein kinase autophosphorylation using expressed protein ligation and computational modeling.Binding mechanism and dynamic conformational change of C subunit of PKA with different pathways.
P2860
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P2860
Crystal structure of the E230Q mutant of cAMP-dependent protein kinase reveals an unexpected apoenzyme conformation and an extended N-terminal A helix.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Crystal structure of the E230Q ...... n extended N-terminal A helix.
@en
type
label
Crystal structure of the E230Q ...... n extended N-terminal A helix.
@en
prefLabel
Crystal structure of the E230Q ...... n extended N-terminal A helix.
@en
P2093
P2860
P356
P1433
P1476
Crystal structure of the E230Q ...... n extended N-terminal A helix.
@en
P2093
Lynn F Ten Eyck
Madhusudan
Natarajan Kannan
Nguyen-Huu Xuong
Susan S Taylor
P2860
P304
P356
10.1110/PS.051715205
P577
2005-11-01T00:00:00Z