LF 16-0687 Ms, a bradykinin B2 receptor antagonist, reduces ischemic brain injury in a murine model of transient focal cerebral ischemia.
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TRPV1 activation results in disruption of the blood-brain barrier in the ratAcute NADPH oxidase activation potentiates cerebrovascular permeability response to bradykinin in ischemia-reperfusion.Bradykinin B2 receptor antagonism: a new direction for acute stroke therapy?The powerful neuroprotective action of C1-inhibitor on brain ischemia-reperfusion injury does not require C1qInhibition of carbonic anhydrase reduces brain injury after intracerebral hemorrhageEffect of Bradykinin Postconditioning on Ischemic and Toxic Brain Damage.Vascular benefits of angiotensin receptor blockers.Kinin B2 receptor regulates chemokines CCL2 and CCL5 expression and modulates leukocyte recruitment and pathology in experimental autoimmune encephalomyelitis (EAE) in mice.Tissue kallikrein in cardiovascular, cerebrovascular and renal diseases and skin wound healing.Involvement of bradykinin in brain edema development after ischemic stroke.The BRAIN TRIAL: a randomised, placebo controlled trial of a Bradykinin B2 receptor antagonist (Anatibant) in patients with traumatic brain injury.Neuroprotective effect of kinin B1 receptor activation in acute cerebral ischemia in diabetic mice.Comparative antagonist pharmacology at the native mouse bradykinin B2 receptor: radioligand binding and smooth muscle contractility studies.Bradykinin-induced astrocyte-neuron signalling: glutamate release is mediated by ROS-activated volume-sensitive outwardly rectifying anion channels.Implication of the Kallikrein-Kinin system in neurological disorders: Quest for potential biomarkers and mechanisms.Omapatrilat: penetration across the blood-brain barrier and effects on ischaemic stroke in rats.Release of bradykinin and expression of kinin B2 receptors in the brain: role for cell death and brain edema formation after focal cerebral ischemia in mice.Opposite roles of bradykinin B1 and B2 receptors during cerebral ischaemia-reperfusion injury in experimental diabetic rats.Tissue kallikrein protects rat hippocampal CA1 neurons against cerebral ischemia/reperfusion-induced injury through the B2R-Raf-MEK1/2-ERK1/2 pathway.Enhancement of bradykinin-induced relaxation by focal brain ischemia in the rat middle cerebral artery: Receptor expression upregulation and activation of multiple pathways.
P2860
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P2860
LF 16-0687 Ms, a bradykinin B2 receptor antagonist, reduces ischemic brain injury in a murine model of transient focal cerebral ischemia.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
LF 16-0687 Ms, a bradykinin B2 ...... sient focal cerebral ischemia.
@en
type
label
LF 16-0687 Ms, a bradykinin B2 ...... sient focal cerebral ischemia.
@en
prefLabel
LF 16-0687 Ms, a bradykinin B2 ...... sient focal cerebral ischemia.
@en
P2093
P2860
P356
P1476
LF 16-0687 Ms, a bradykinin B2 ...... sient focal cerebral ischemia.
@en
P2093
Bruno Palmier
Catherine Marchand-Verrecchia
Didier Pruneau
Isabelle Margaill
Li Ding-Zhou
Michel Plotkine
P2860
P304
P356
10.1038/SJ.BJP.0705385
P407
P577
2003-08-01T00:00:00Z