Agonist activation of transfected human M1 muscarinic acetylcholine receptors in CHO cells results in down-regulation of both the receptor and the alpha subunit of the G-protein Gq.
about
Agonist-induced transfer of the alpha subunits of the guanine-nucleotide-binding regulatory proteins Gq and G11 and of muscarinic m1 acetylcholine receptors from plasma membranes to a light-vesicular membrane fractionInhibition of KCNQ1-4 potassium channels expressed in mammalian cells via M1 muscarinic acetylcholine receptorsDifferential tetraethylammonium sensitivity of KCNQ1-4 potassium channelsAlternative splicing of KCNQ2 potassium channel transcripts contributes to the functional diversity of M-currents.Muscarinic acetylcholine receptor down-regulation limits the extent of inhibition of cell cycle progression in Chinese hamster ovary cells.Gonadotrophin-releasing hormone receptor agonist-mediated down-regulation of Gq alpha/G11 alpha (pertussis toxin-insensitive) G proteins in alpha T3-1 gonadotroph cells reflects increased G protein turnover but not alterations in mRNA levels.PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identitySelective Membrane Redistribution and Depletion of Gαq-Protein by Pasteurella multocida ToxinMaintenance of Y receptor dimers in epithelial cells depends on interaction with G-protein heterotrimers.Contrasting effects of phorbol ester and agonist-mediated activation of protein kinase C on phosphoinositide and Ca2+ signalling in a human neuroblastomaG(o)-protein alpha-subunits activate mitogen-activated protein kinase via a novel protein kinase C-dependent mechanism.Beta 3-adrenoceptor agonist-induced down-regulation of Gs alpha and functional desensitization in a Chinese hamster ovary cell line expressing a beta 3-adrenoceptor refractory to down-regulation.Distinct subunit contributions to the activation of M-type potassium channels by PI(4,5)P2.Agonist regulation of cellular Gs alpha-subunit levels in neuroblastoma x glioma hybrid NG108-15 cells transfected to express different levels of the human beta 2 adrenoceptor.Down-regulation of the G-proteins Gq alpha and G11 alpha by transfected human M3 muscarinic acetylcholine receptors in Chinese hamster ovary cells is independent of receptor down-regulation.Regulation of the human histamine H1 receptor stably expressed in Chinese hamster ovary cells.Biochemical changes contributing to functional quiescence in lacrimal gland acinar cells after chronic ex vivo exposure to a muscarinic agonist.Enhanced degradation of the phosphoinositidase C-linked guanine-nucleotide-binding protein Gq alpha/G11 alpha following activation of the human M1 muscarinic acetylcholine receptor expressed in CHO cells.Membrane-Bound and cytosolic forms of heterotrimeric G proteins in young and adult rat myocardium: influence of neonatal hypo- and hyperthyroidism.Opposing short- and long-term effects on muscarinic M1/4 receptor binding following chronic phencyclidine treatment.Equivalent regulation of wild type and an epitope-tagged variant of Gs alpha by the IP prostanoid receptor following expression in neuroblastoma x glioma hybrid, NG108-15, cells.Chronic ethanol reduces immunologically detectable Gq alpha/11 alpha in NG108-15 cells.The human muscarinic M1 acetylcholine receptor, when expressed in CHO cells, activates and downregulates both Gqα and G11α equally and non-selectively
P2860
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P2860
Agonist activation of transfected human M1 muscarinic acetylcholine receptors in CHO cells results in down-regulation of both the receptor and the alpha subunit of the G-protein Gq.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Agonist activation of transfec ...... a subunit of the G-protein Gq.
@en
type
label
Agonist activation of transfec ...... a subunit of the G-protein Gq.
@en
prefLabel
Agonist activation of transfec ...... a subunit of the G-protein Gq.
@en
P2093
P2860
P356
P1433
P1476
Agonist activation of transfec ...... a subunit of the G-protein Gq.
@en
P2093
P2860
P304
P356
10.1042/BJ2890125
P407
P478
289 ( Pt 1)
P577
1993-01-01T00:00:00Z