Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells. - Wikidata - wikimedia - TriplyDB

Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells.

Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells.

http://www.wikidata.org/entity/Q41773432

about

Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells Antiviral CD4+ memory T cells are IL-15 dependent Infection as an Environmental Trigger of Multiple Sclerosis Disease Exacerbation CD8(+)CD122(+) T-Cells: A Newly Emerging Regulator with Central Memory Cell Phenotypes Ly49 receptors: innate and adaptive immune paradigms T cell memory in the context of persistent herpes viral infections The suppression of immune system disorders by passive attrition New insights into the regulation of T cells by gamma(c) family cytokines Diacylglycerol Kinase ζ Limits Cytokine-dependent Expansion of CD8+ T Cells with Broad Antitumor Capacity.Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells Global transcriptome-wide analysis of CIK cells identify distinct roles of IL-2 and IL-15 in acquisition of cytotoxic capacity against tumor.Development and function of invariant natural killer T cells producing T(h)2- and T(h)17-cytokines Strategies to use immune modulators in therapeutic vaccines against cancer CD4+ T cells are required for the maintenance, not programming, of memory CD8+ T cells after acute infection.Simultaneous blockade of multiple immune system inhibitory checkpoints enhances antitumor activity mediated by interleukin-15 in a murine metastatic colon carcinoma model Sinks, suppressors and antigen presenters: how lymphodepletion enhances T cell-mediated tumor immunotherapy.IL-15 augments TCR-induced CD4+ T cell expansion in vitro by inhibiting the suppressive function of CD25 High CD4+ T cells.TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells.Altered IL-7Ralpha expression with aging and the potential implications of IL-7 therapy on CD8+ T-cell immune responses.CD8+ T regulatory cells express the Ly49 Class I MHC receptor and are defective in autoimmune prone B6-Yaa mice.Regulating functional cell fates in CD8 T cells.Converting IL-15 to a superagonist by binding to soluble IL-15R{alpha}The TCR's sensitivity to self peptide-MHC dictates the ability of naive CD8(+) T cells to respond to foreign antigens.A central role for mTOR kinase in homeostatic proliferation induced CD8+ T cell memory and tumor immunity Surviving the crash: transitioning from effector to memory CD8+ T cell.IL-15R alpha expression on CD8+ T cells is dispensable for T cell memory Gammaherpesvirus persistence alters key CD8 T-cell memory characteristics and enhances antiviral protection CD40 is required for protective immunity against liver stage Plasmodium infection IL-7 regulates basal homeostatic proliferation of antiviral CD4+T cell memory.Different functional capacities of latent and lytic antigen-specific CD8 T cells in murine gammaherpesvirus infection.In remembrance of things past: memory T cells and transplant rejection.Overexpression of IL-15 promotes tumor destruction via NK1.1+ cells in a spontaneous breast cancer model.Type I interferons regulate eomesodermin expression and the development of unconventional memory CD8(+) T cells.TLR agonists and/or IL-15 adjuvanted mucosal SIV vaccine reduced gut CD4⁺ memory T cell loss in SIVmac251-challenged rhesus macaques.Molecular adjuvants for mucosal immunity.Homeostatic expansion and repertoire regeneration of donor T cells during graft versus host disease is constrained by the host environment.Stress-activated Dendritic Cells (DC) Induce Dual Interleukin (IL)-15- and IL1β-mediated Pathways, Which May Elicit CD4+ Memory T Cells and Interferon (IFN)-stimulated Genes.A push-pull vaccine strategy using Toll-like receptor ligands, IL-15, and blockade of negative regulation to improve the quality and quantity of T cell immune responses.Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model.

P2860

Q24540135-E14ED012-9896-4451-AE4D-8037628DB004 Q24621753-4C5B0F3B-A7ED-4D2F-ABC4-BD91DAE2869D Q24676283-2FD6E7FC-BED6-4554-9A69-AF116DD98B79 Q26779416-3367A011-2FFB-4EA7-B994-4502EB8A27C6 Q26779422-AACD0197-73D6-4C5F-984C-E7053D2818A8 Q26825078-072D510F-13C5-4FF4-9FEB-B55E65CBD709 Q26999125-BC402996-7741-41ED-BDB4-A057D5C76A09 Q33543065-3FFE18B1-1E04-49B3-B850-2567751161E7 Q33623326-FD0A1FB8-6E3B-48EE-A8CF-89712E1C91DE Q33715829-8D433482-1859-4B45-993B-27B2DDF51610 Q33831940-2DF4D206-58C6-4A94-A746-B4017C54F134 Q34050208-08B49CBA-21A4-476F-AB5C-6A3BBBFA9319 Q34162198-FBEB18E5-FAF2-4E2E-9E1D-814CDB54512E Q34275601-370DB7A1-2DD1-4DEE-919D-26E4A6BA1274 Q34339494-44EAC697-2616-4327-AEFC-2ACFBFE48FFA Q34420239-7DB75D65-650A-42AD-934E-3CE812BFEE9D Q34422330-AFF0FD08-84D4-41F2-ADD7-BBFAA5AC83F2 Q34428659-3B8F5C80-C71E-4C89-A275-7DB9289C731B Q34468344-37739C54-F658-484A-851C-12BBBD55B6EC Q34546812-60E8959E-BCA6-4B1B-AC71-F9963D62C68C Q34550146-66953785-FE0B-4BA4-AC16-1BFD352FF5AD Q34613183-FD57FBC8-A564-45E9-A98D-69F8D8B65A73 Q34694913-2D3EC827-59C7-481E-8DA0-DABF8E43D6AC Q34734561-EF131A57-0097-4DC0-A22B-58CEB71F4798 Q34876814-9643EF78-92DE-4D33-94FD-DFC408902C3B Q34958560-ECC9FA62-9E95-4FDB-80EA-3FE7940F84BF Q34960007-5C654CC9-EE64-4A41-8F4C-39E14DBBC9CC Q35024174-DADA5129-899D-4CAA-8FB9-9BFF5E72EF07 Q35122368-C9E4101C-46CA-4173-B707-B9E3B593205E Q35319176-751852CD-BF99-4A6C-A393-070060AF7782 Q35444588-854D1510-6870-44DF-B89F-D38E3554D26C Q35583502-BAEEF94A-1E93-4874-A67E-A6E8AF55E1FA Q35595605-0058EBFD-AE0E-4022-92AD-A1F81BC7D03D Q35608970-8871A921-DA59-4C79-8127-1783C3A409CB Q35672335-A246490A-2067-4E55-ACB9-137A1E271C78 Q35826381-AC93CACF-2124-4947-B227-3E4909B95E57 Q35839841-125E8700-1036-4FCE-AC16-BD1BF0B1AE11 Q35860660-A9C53F5E-1146-4A12-A406-64D45A5E7F3C Q35871793-647D49A1-8402-4C02-89AA-1A8755282880 Q35924987-E4425236-1E22-4C9C-A0A9-029D6C819F83

P2860

Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells.

http://www.wikidata.org/entity/Q41773432

description

2002 nî lūn-bûn

@nan

2002年の論文

@ja

2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

2002年论文

@zh

2002年论文

@zh-cn

name

Interleukin 15 controls both p ...... mory-phenotype CD8(+) T cells.

@en

type

label

Interleukin 15 controls both p ...... mory-phenotype CD8(+) T cells.

@en

prefLabel

Interleukin 15 controls both p ...... mory-phenotype CD8(+) T cells.

@en

P1433

Q41773432-07621E95-5A2A-470E-8689-0C4778E8AA09

P1476

Q41773432-02D0CBC3-29D4-4D44-A494-5F70A377E1C9

P2093

Q41773432-13D4BDA7-C273-416B-BB72-3CDFE2693B5B

Q41773432-565606B9-2046-4C25-A732-6CD40C57D4CB

Q41773432-84614ACC-0F61-47DB-8873-83BCE431A661

Q41773432-882F4972-5E19-445A-A4FE-73363E17394D

P2860

Q41773432-07DE4AD9-BDA3-46F3-9C6F-5EC298FC676D

Q41773432-106B6F14-B2AE-42FD-AB1E-EE783075168E

Q41773432-1989DC4B-4193-4E92-8FA7-F1B3E64EB723

Q41773432-1DA17AA8-E849-43F5-9AA6-6A11CC2BD4E7

Q41773432-20F7FF78-F17D-4344-A693-D7B2A09BEABC

Q41773432-22150FD0-CE59-439F-AF07-2F3BEC29A2BC

Q41773432-2B2D9012-A1FD-48F1-8039-C2B99D0D0F45

Q41773432-2F1FD6F6-B4FC-494B-B716-221161E8207D

Q41773432-44C9F205-8485-4283-B651-2BDBA552995F

Q41773432-454D42B6-FD46-48B8-8997-DEEBCE2B815E

P304

Q41773432-7D5B043B-8BDC-4F15-B34A-C736086D079F

P31

Q41773432-811F47F2-C342-402F-994D-298CC399E824

P356

Q41773432-580F4B4A-A02E-4E67-9D2E-6C6213B974D0

P407

Q41773432-69ED173C-AF90-4DBC-9A76-31CD21827DEA

P433

Q41773432-2BA22547-EDF4-4ECC-A7B6-9F5F749A7846

P478

Q41773432-081531CC-0CD5-4406-9595-E41C76217D98

P50

Q41773432-6319E614-6985-4865-8098-09E7B9760972

P577

Q41773432-5A64C6CC-D998-4804-A8C5-FF311DBCC8BF

P5875

Q41773432-37D6EE2A-2932-4227-B28D-AE7C2CD8CFDA

P698

Q41773432-FDCCC4C2-FF05-40CF-A124-4E29F3E4F78A

P932

Q41773432-AFD6B04E-C6B6-45FE-BC11-F79596E66D56

P356

P1433

Journal of Experimental Medicine

P1476

Interleukin 15 controls both p ...... mory-phenotype CD8(+) T cells.

@en

P2093

Adam D Judge

http://www.w3.org/2001/XMLSchema#string

Charles D Surh

http://www.w3.org/2001/XMLSchema#string

Hideki Fujii

http://www.w3.org/2001/XMLSchema#string

Xiaohong Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivo

The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens

IL-15 is expressed by dendritic cells in response to type I IFN, double-stranded RNA, or lipopolysaccharide and promotes dendritic cell activation

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

T-cell proliferation in vivo and the role of cytokines

Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo.

Generation and maintenance of memory T cells.

Regulation of the natural killer cell receptor repertoire.

Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells.

Potent induction of long-term CD8+ T cell memory by short-term IL-4 exposure during T cell receptor stimulation.

P304

935-946

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1084/JEM.20020772

http://www.w3.org/2001/XMLSchema#string

P407

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

196

http://www.w3.org/2001/XMLSchema#string

P50

Jonathan Sprent

P577

2002-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

11090022

http://www.w3.org/2001/XMLSchema#string

P698

12370255

http://www.w3.org/2001/XMLSchema#string

P932

2194030

http://www.w3.org/2001/XMLSchema#string