Identification of DYRK1B as a substrate of ERK1/2 and characterisation of the kinase activity of DYRK1B mutants from cancer and metabolic syndrome.
about
DYRK1B mutations associated with metabolic syndrome impair the chaperone-dependent maturation of the kinase domain.High Expression of Phosphorylated Extracellular Signal-Regulated Kinase (ERK1/2) is Associated with Poor Prognosis in Newly Diagnosed Patients with Multiple Myeloma.A wake-up call to quiescent cancer cells - potential use of DYRK1B inhibitors in cancer therapy.
P2860
Identification of DYRK1B as a substrate of ERK1/2 and characterisation of the kinase activity of DYRK1B mutants from cancer and metabolic syndrome.
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
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2015年论文
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2015年论文
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2015年论文
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name
Identification of DYRK1B as a ...... cancer and metabolic syndrome.
@en
type
label
Identification of DYRK1B as a ...... cancer and metabolic syndrome.
@en
prefLabel
Identification of DYRK1B as a ...... cancer and metabolic syndrome.
@en
P2093
P2860
P1476
Identification of DYRK1B as a ...... cancer and metabolic syndrome
@en
P2093
Anne L Ashford
Kathryn Balmanno
Kevin Hudson
Lisa M Baak
Louise M Goodwin
Mark Cockerill
Pamela A Lochhead
Rachel A Rowlinson
Raffaella Gallo
Richard A Ward
P2860
P2888
P304
P356
10.1007/S00018-015-2032-X
P50
P577
2015-09-07T00:00:00Z