Acidic phospholipids inhibit the intramolecular association between the N- and C-terminal regions of vinculin, exposing actin-binding and protein kinase C phosphorylation sites.
about
Vinexin: a novel vinculin-binding protein with multiple SH3 domains enhances actin cytoskeletal organizationConformation, localization, and integrin binding of talin depend on its interaction with phosphoinositidesThe focal-adhesion vasodilator-stimulated phosphoprotein (VASP) binds to the proline-rich domain in vinculinalpha-Catenin-vinculin interaction functions to organize the apical junctional complex in epithelial cellsRecruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesionRaver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteinsDimer asymmetry defines α-catenin interactionsThe epidermal growth factor receptor modulates the interaction of E-cadherin with the actin cytoskeletonSerine 34 phosphorylation of rho guanine dissociation inhibitor (RhoGDIalpha) links signaling from conventional protein kinase C to RhoGTPase in cell adhesion.The F-actin cross-linking and focal adhesion protein filamin A is a ligand and in vivo substrate for protein kinase C alphaVinculin directly binds zonula occludens-1 and is essential for stabilizing connexin-43-containing gap junctions in cardiac myocytesMultimerization of the cytoplasmic domain of syndecan-4 is required for its ability to activate protein kinase CA lipid-regulated docking site on vinculin for protein kinase C.Protein-lipid interactions: correlation of a predictive algorithm for lipid-binding sites with three-dimensional structural dataAmphitropic proteins: regulation by reversible membrane interactions (review).Talin contains three similar vinculin-binding sites predicted to form an amphipathic helixVinculin in cell-cell and cell-matrix adhesions.Myosin II activity dependent and independent vinculin recruitment to the sites of E-cadherin-mediated cell-cell adhesion.Molecular basis of the intracellular spreading of Shigella.Comparative biochemical analysis suggests that vinculin and metavinculin cooperate in muscular adhesion sites.Morphologic responses of endothelium to shear stress: reorganization of the adherens junction.Lipid binding promotes oligomerization and focal adhesion activity of vinculinVinculin and talin: focus on the myocardiumHAb18G/CD147 regulates vinculin-mediated focal adhesion and cytoskeleton organization in cultured human hepatocellular carcinoma cells.New insights into vinculin function and regulation.The vinculin C-terminal hairpin mediates F-actin bundle formation, focal adhesion, and cell mechanical properties.The C-terminal tail domain of metavinculin, vinculin's splice variant, severs actin filaments.Vinculin proteolysis unmasks an ActA homolog for actin-based Shigella motility.Vinculin is part of the cadherin-catenin junctional complex: complex formation between alpha-catenin and vinculin.Integrin-mediated signals regulated by members of the rho family of GTPases.Mechano-coupling and regulation of contractility by the vinculin tail domainLipid binding to the tail domain of vinculin: specificity and the role of the N and C termini.Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerizationVinculin nucleates actin polymerization and modifies actin filament structure.The role of vinculin in the regulation of the mechanical properties of cells.The phosphorylation of vinculin on tyrosine residues 100 and 1065, mediated by SRC kinases, affects cell spreading.Vinculin phosphorylation at Tyr1065 regulates vinculin conformation and tension development in airway smooth muscle tissues.Vinculin, an adapter protein in control of cell adhesion signalling.Mechanisms and Functions of Vinculin Interactions with Phospholipids at Cell Adhesion Sites.Interaction of the N- and C-terminal domains of vinculin. Characterization and mapping studies.
P2860
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P2860
Acidic phospholipids inhibit the intramolecular association between the N- and C-terminal regions of vinculin, exposing actin-binding and protein kinase C phosphorylation sites.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Acidic phospholipids inhibit t ...... inase C phosphorylation sites.
@en
type
label
Acidic phospholipids inhibit t ...... inase C phosphorylation sites.
@en
prefLabel
Acidic phospholipids inhibit t ...... inase C phosphorylation sites.
@en
P2093
P2860
P356
P1433
P1476
Acidic phospholipids inhibit t ...... inase C phosphorylation sites.
@en
P2093
P2860
P304
P356
10.1042/BJ3140827
P407
P478
314 ( Pt 3)
P577
1996-03-01T00:00:00Z