CD22-antagonists with nanomolar potency: the synergistic effect of hydrophobic groups at C-2 and C-9 of sialic acid scaffold
about
From a library of MAG antagonists to nanomolar CD22 ligands.High affinity sialoside ligands of myelin associated glycoprotein.Steering Siglec-Sialic Acid Interactions on Living Cells using Bioorthogonal Chemistry.CD22 and Siglec-G regulate inhibition of B-cell signaling by sialic acid ligand binding and control B-cell tolerance.Therapeutic Targeting of Siglecs using Antibody- and Glycan-Based Approaches.New Human CD22/Siglec-2 Ligands with a Triazole Glycoside.Extensive crosslinking of CD22 by epratuzumab triggers BCR signaling and caspase-dependent apoptosis in human lymphoma cells.Disubstituted Sialic Acid Ligands Targeting Siglecs CD33 and CD22 Associated with Myeloid Leukaemias and B Cell Lymphomas.Structural characterisation of high affinity Siglec-2 (CD22) ligands in complex with whole Burkitt's lymphoma (BL) Daudi cells by NMR spectroscopyCD22-Binding Synthetic Sialosides Regulate B Lymphocyte Proliferation Through CD22 Ligand-Dependent and Independent Pathways, and Enhance Antibody Production in Mice.
P2860
Q31032076-C13CF3EE-6152-41CC-99CC-FE1217F21E8DQ35165362-040A3557-0303-460C-B4EE-A228496738F7Q36279536-13BEE338-CC86-46AB-8016-DEF1FD765E3AQ38227144-F0924CE2-0BAF-42F4-BADD-751C5B71E73BQ38598881-F5F73BBA-A797-488E-99C0-FE58793173A3Q38709008-AB963685-A608-4624-A5A5-D3C18B77D792Q38931196-58CA82B7-B04B-4C48-9680-368B3C09D8A1Q40415354-6264E469-EFBB-42E0-BEF6-06AE4C9ABA65Q42374807-22EDBE54-3CC0-4CB2-96DA-F6C335B266E8Q54937363-916840BC-39AB-49A0-9707-8AC929932FC4
P2860
CD22-antagonists with nanomolar potency: the synergistic effect of hydrophobic groups at C-2 and C-9 of sialic acid scaffold
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
CD22-antagonists with nanomola ...... nd C-9 of sialic acid scaffold
@en
type
label
CD22-antagonists with nanomola ...... nd C-9 of sialic acid scaffold
@en
prefLabel
CD22-antagonists with nanomola ...... nd C-9 of sialic acid scaffold
@en
P2093
P2860
P1476
CD22-antagonists with nanomola ...... nd C-9 of sialic acid scaffold
@en
P2093
Chiaki Takaku
Gladys C Completo
Hajjaj H M Abdu-Allah
Hideharu Ishida
Hiromu Takematsu
Hiromune Ando
James C Paulson
Koji Hayashizaki
Kozo Watanabe
Magesh Sadagopan
P2860
P304
P356
10.1016/J.BMC.2011.01.060
P407
P577
2011-02-02T00:00:00Z