Variations in aggrecan structure modulate its susceptibility to aggrecanases.
about
ADAMTS-4 and ADAMTS-5: key enzymes in osteoarthritis.ADAMTS-5 deficiency does not block aggrecanolysis at preferred cleavage sites in the chondroitin sulfate-rich region of aggrecan.MMPs are less efficient than ADAMTS5 in cleaving aggrecan core protein.Involvement of ADAMTS5 and hyaluronidase in aggrecan degradation and release from OSM-stimulated cartilageAggrecan heterogeneity in articular cartilage from patients with osteoarthritis.The role of aggrecan in normal and osteoarthritic cartilage.Selective and non-selective metalloproteinase inhibitors reduce IL-1-induced cartilage degradation and loss of mechanical properties.Osteopontin can decrease the expression of Col-II and COMP in cartilage cells in vitro.Distinguishing aggrecan loss from aggrecan proteolysis in ADAMTS-4 and ADAMTS-5 single and double deficient mice.Keratan Sulphate, a complex Glycosaminoglycan with Unique Functional Capability.Aggrecanase analysis of synovial fluid of temporomandibular joint disorders.
P2860
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P2860
Variations in aggrecan structure modulate its susceptibility to aggrecanases.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Variations in aggrecan structure modulate its susceptibility to aggrecanases.
@en
type
label
Variations in aggrecan structure modulate its susceptibility to aggrecanases.
@en
prefLabel
Variations in aggrecan structure modulate its susceptibility to aggrecanases.
@en
P2093
P2860
P356
P1433
P1476
Variations in aggrecan structure modulate its susceptibility to aggrecanases.
@en
P2093
Fengrong Zuo
James Barnett
John S Mort
Peter J Roughley
P2860
P304
P356
10.1042/BJ20030609
P407
P577
2003-10-01T00:00:00Z