Diabetes-induced coronary vascular dysfunction involves increased arginase activity
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The Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular DiseasePrinciples of targeting endothelial cell metabolism to treat angiogenesis and endothelial cell dysfunction in diseaseArginase as a Critical Prooxidant Mediator in the Binomial Endothelial Dysfunction-AtherosclerosisTargeting Nitric Oxide with Natural Derived Compounds as a Therapeutic Strategy in Vascular DiseasesEx vivo and in vitro effect of serum amyloid a in the induction of macrophage M2 markers and efferocytosis of apoptotic neutrophilsSelective endothelial overexpression of arginase II induces endothelial dysfunction and hypertension and enhances atherosclerosis in miceArginase promotes endothelial dysfunction and hypertension in obese ratsIntravenous administration of piceatannol, an arginase inhibitor, improves endothelial dysfunction in aged miceSepiapterin decreases acute rejection and apoptosis in cardiac transplants independently of changes in nitric oxide and inducible nitric-oxide synthase dimerization.Diabetes-induced inhibition of voltage-dependent calcium channels in the retinal microvasculature: role of spermine.Diabetic retinopathy: current management and experimental therapeutic targets.Reduced nitro-oxidative stress and neural cell death suggests a protective role for microglial cells in TNFalpha-/- mice in ischemic retinopathy.Role for high-glucose-induced protein O-GlcNAcylation in stimulating cardiac fibroblast collagen synthesisVascular dysfunction in retinopathy-an emerging role for arginaseMicroRNA regulation in Ames dwarf mouse liver may contribute to delayed aging.Mitochondrial targeting by dichloroacetate improves outcome following hemorrhagic shock.Thrombin induces endothelial arginase through AP-1 activation.Endothelial arginine resynthesis contributes to the maintenance of vasomotor function in male diabetic mice.Estrogen and oxidative stress: A novel mechanism that may increase the risk for cardiovascular disease in women.Arginase inhibition ameliorates hepatic metabolic abnormalities in obese mice.Arginase 2 deletion reduces neuro-glial injury and improves retinal function in a model of retinopathy of prematurity.The role of arginase and rho kinase in cardioprotection from remote ischemic perconditioning in non-diabetic and diabetic rat in vivo.Reduced LDL-cholesterol levels in patients with coronary artery disease are paralleled by improved endothelial function: An observational study in patients from 2003 and 2007Novel therapeutic strategies for adult obese asthmatics.Rho/Rho-associated coiled-coil forming kinase pathway as therapeutic targets for statins in atherosclerosis.Local arginase inhibition during early reperfusion mediates cardioprotection via increased nitric oxide production.p38 Mitogen-activated protein kinase (MAPK) increases arginase activity and contributes to endothelial dysfunction in corpora cavernosa from angiotensin-II-treated miceFunctions of arginase isoforms in macrophage inflammatory responses: impact on cardiovascular diseases and metabolic disorders.Arginase 2 deficiency prevents oxidative stress and limits hyperoxia-induced retinal vascular degeneration.The role of arginase I in diabetes-induced retinal vascular dysfunction in mouse and rat models of diabetes.New approaches to the design and discovery of therapies to prevent erectile dysfunction.Arginase 1 contributes to diminished coronary arteriolar dilation in patients with diabetesNitrite-generated NO circumvents dysregulated arginine/NOS signaling to protect against intimal hyperplasia in Sprague-Dawley ratsIncreased erythrocytes by-products of arginine catabolism are associated with hyperglycemia and could be involved in the pathogenesis of type 2 diabetes mellitus.Arginase in retinopathy.Nitric oxide synthetic pathway in red blood cells is impaired in coronary artery disease.Akita spontaneously type 1 diabetic mice exhibit elevated vascular arginase and impaired vascular endothelial and nitrergic function.Angiotensin II-induced vascular endothelial dysfunction through RhoA/Rho kinase/p38 mitogen-activated protein kinase/arginase pathway.Recent advances in arginine metabolism: roles and regulation of the arginases.Arginase II deletion increases corpora cavernosa relaxation in diabetic mice.
P2860
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P2860
Diabetes-induced coronary vascular dysfunction involves increased arginase activity
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Diabetes-induced coronary vascular dysfunction involves increased arginase activity
@en
type
label
Diabetes-induced coronary vascular dysfunction involves increased arginase activity
@en
prefLabel
Diabetes-induced coronary vascular dysfunction involves increased arginase activity
@en
P2093
P2860
P1433
P1476
Diabetes-induced coronary vascular dysfunction involves increased arginase activity
@en
P2093
Azza B El-Remessy
Daniel H Platt
Huda E Tawfik
Manuela Bartoli
Maritza J Romero
Mohamed Labazi
Robert W Caldwell
Ruth B Caldwell
P2860
P304
P356
10.1161/CIRCRESAHA.107.155028
P577
2007-10-25T00:00:00Z