Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1. - Wikidata - wikimedia - TriplyDB

Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1.

Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1.

http://www.wikidata.org/entity/Q41834963

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Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteins Crystal Structure of the Geobacillus stearothermophilus Carboxylesterase Est55 and Its Activation of Prodrug CPT-11 Crystal Structures of Human Carboxylesterase 1 in Covalent Complexes with the Chemical Warfare Agents Soman and Tabun † , ‡Structure of recombinant human carboxylesterase 1 isolated from whole cabbage looper larvae Pharmacodynamic Impact of Carboxylesterase 1 Gene Variants in Patients with Congestive Heart Failure Treated with Angiotensin-Converting Enzyme Inhibitors Horse carboxylesterases: evidence for six CES1 and four families of CES genes on chromosome 3 Mammalian carboxylesterase 3: comparative genomics and proteomics Baboon carboxylesterases 1 and 2: sequences, structures and phylogenetic relationships with human and other primate carboxylesterases Bovine Carboxylesterases: Evidence for Two CES1 and Five Families of CES Genes on Chromosome 18 Opossum carboxylesterases: sequences, phylogeny and evidence for CES gene duplication events predating the marsupial-eutherian common ancestor Individualization of treatments with drugs metabolized by CES1: combining genetics and metabolomics.Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides: role of carboxylesterases 1 and 2 Porcine Liver Carboxylesterase Requires Polyisoprenylation for High Affinity Binding to Cysteinyl Substrates.Esterase-activated release of naproxen from supramolecular nanofibres.Reactivity versus steric effects in fluorinated ketones as esterase inhibitors: a quantum mechanical and molecular dynamics study Carboxylesterase 1 gene duplication and mRNA expression in adipose tissue are linked to obesity and metabolic function Comparison of the Structure and Activity of Glycosylated and Aglycosylated Human Carboxylesterase 1 Substrate-Competitive Activity-Based Profiling of Ester Prodrug Activating Enzymes Inhibition of carboxylesterase 1 is associated with cholesteryl ester retention in human THP-1 monocyte/macrophages.Mammalian carboxylesterase 5: comparative biochemistry and genomics.Regulation of carboxylesterase 1 (CES1) in human adipose tissue A new class of mammalian carboxylesterase CES6.Genetics, physiology and perinatal influences in childhood obesity: view from the Chair.Inhibition of carboxylesterase activity of THP1 monocytes/macrophages and recombinant human carboxylesterase 1 by oxysterols and fatty acids.Biochemical and docking analysis of substrate interactions with polyisoprenylated methylated protein methyl esterase.Carboxylesterase inhibitors.Carboxylesterases: General detoxifying enzymes.Improving the 'tool box' for robust industrial enzymes.Effects of toxicologically relevant xenobiotics and the lipid-derived electrophile 4-hydroxynonenal on macrophage cholesterol efflux: silencing carboxylesterase 1 has paradoxical effects on cholesterol uptake and efflux.Labeling of Cellular DNA with a Cyclosal Phosphotriester Pronucleotide Analog of 5-ethynyl-2'-deoxyuridine.Identification of gallic acid based glycoconjugates as a novel tubulin polymerization inhibitors.Structural and biochemical characterisation of Archaeoglobus fulgidus esterase reveals a bound CoA molecule in the vicinity of the active site.Immobilization of active human carboxylesterase 1 in biomimetic silica nanoparticles.Regulation of polyisoprenylated methylated protein methyl esterase by polyunsaturated fatty acids and prostaglandins.Polyisoprenylation potentiates the inhibition of polyisoprenylated methylated protein methyl esterase and the cell degenerative effects of sulfonyl fluorides.Comparison of benzil and trifluoromethyl ketone (TFK)-mediated carboxylesterase inhibition using classical and 3D-quantitative structure-activity relationship analysis.Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin.Comparative study of the hydrolytic metabolism of methyl-, ethyl-, propyl-, butyl-, heptyl- and dodecylparaben by microsomes of various rat and human tissues.The Mycobacterium tuberculosis Ag85A is a novel diacylglycerol acyltransferase involved in lipid body formation.Evaluation of the 'side door' in carboxylesterase-mediated catalysis and inhibition.

P2860

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P2860

Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1.

http://www.wikidata.org/entity/Q41834963

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2006 nî lūn-bûn

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2006年の論文

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2006年論文

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2006年论文

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2006年论文

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Multisite promiscuity in the p ...... s by human carboxylesterase 1.

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Multisite promiscuity in the p ...... s by human carboxylesterase 1.

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Multisite promiscuity in the p ...... s by human carboxylesterase 1.

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J.JMB.2006.08.025

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Journal of Molecular Biology

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Multisite promiscuity in the p ...... s by human carboxylesterase 1.

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Carol C Edwards

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Christopher L Morton

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Escher L Howard-Williams

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Peter Kuhn

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Sompop Bencharit

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P2860

Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone

Improved methods for building protein models in electron density maps and the location of errors in these models

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

The crystal structure of palmitoyl protein thioesterase 1 and the molecular basis of infantile neuronal ceroid lipofuscinosis

Structural basis for the insensitivity of a serine enzyme (palmitoyl-protein thioesterase) to phenylmethylsulfonyl fluoride

Crystal structure of the catalytic domain of human bile salt activated lipase

Crystal structure of the human acyl protein thioesterase I from a single X-ray data set to 1.5 A

Structural insights into CPT-11 activation by mammalian carboxylesterases

Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme

Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: from binding promiscuity to selective inhibition

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1762004

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