Double-blind, randomized, placebo-controlled study of safety, tolerability, pharmacokinetics and pharmacodynamics of TAK-683, an investigational metastin analogue in healthy men.
about
The kisspeptin-GnRH pathway in human reproductive health and diseaseAn administration of TAK-683 at a minimally effective dose for luteinizing hormone stimulation under the absence of the ovary induces luteinizing hormone surge in ovary-intact goatsKisspeptin receptor agonist (FTM080) increased plasma concentrations of luteinizing hormone in anestrous ewes.A synthetic kisspeptin analog that triggers ovulation and advances pubertyDifferential effects of continuous exposure to the investigational metastin/kisspeptin analog TAK-683 on pulsatile and surge mode secretion of luteinizing hormone in ovariectomized goats.The pharmacotherapy of male hypogonadism besides androgens.Kisspeptin signalling in the physiology and pathophysiology of the urogenital system.Neuropeptide derivatives to regulate the reproductive axis: Kisspeptin receptor (KISS1R) ligands and neurokinin-3 receptor (NK3R) ligands.Effects of the Hormone Kisspeptin on Reproductive Hormone Release in Humans
P2860
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P2860
Double-blind, randomized, placebo-controlled study of safety, tolerability, pharmacokinetics and pharmacodynamics of TAK-683, an investigational metastin analogue in healthy men.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Double-blind, randomized, plac ...... astin analogue in healthy men.
@en
type
label
Double-blind, randomized, plac ...... astin analogue in healthy men.
@en
prefLabel
Double-blind, randomized, plac ...... astin analogue in healthy men.
@en
P2093
P2860
P1476
Double-blind, randomized, plac ...... astin analogue in healthy men.
@en
P2093
Cristina Oliva
Darren Wilbraham
David MacLean
Graham Scott
Irfan Ahmad
Katy Howard
Paul Worthington
Steve Warrington
P2860
P304
P356
10.1111/J.1365-2125.2012.04385.X
P407
P577
2013-02-01T00:00:00Z