about
Radiation-induced alterations in histone modification patterns and their potential impact on short-term radiation effectsFunctions of PARylation in DNA Damage Repair PathwaysRoles of RNA-Binding Proteins in DNA Damage ResponseBeyond DNA repair: DNA-PK function in cancerPleiotropic cellular functions of PARP1 in longevity and aging: genome maintenance meets inflammationSystems modelling of NHEJ reveals the importance of redox regulation of Ku70/80 in the dynamics of dna damage fociStructural Basis for DNA Damage-Dependent Poly(ADP-ribosyl)ation by Human PARP-1TNKS1BP1 functions in DNA double-strand break repair though facilitating DNA-PKcs autophosphorylation dependent on PARP-1Strategies for the Use of Poly(adenosine diphosphate ribose) Polymerase (PARP) Inhibitors in Cancer Therapy.Alternative splicing of FBP-interacting repressor coordinates c-Myc, P27Kip1/cyclinE and Ku86/XRCC5 expression as a molecular sensor for bleomycin-induced DNA damage pathway.Inhibition of DNA damage repair by artificial activation of PARP with siDNA.New paradigms in the repair of oxidative damage in human genome: mechanisms ensuring repair of mutagenic base lesions during replication and involvement of accessory proteins.Quantitative proteomics profiling of the poly(ADP-ribose)-related response to genotoxic stress.Therapeutic applications of PARP inhibitors: anticancer therapy and beyondStructure of the intact ATM/Tel1 kinase.Predictive biomarkers for cancer therapy with PARP inhibitors.Poly(ADP-ribosyl)ation in regulation of chromatin structure and the DNA damage response.The spatial organization of non-homologous end joining: from bridging to end joining.The rise and fall of poly(ADP-ribose): An enzymatic perspective.Estrogens regulate life and death in mitochondria.TDP1 promotes assembly of non-homologous end joining protein complexes on DNA.Cryo-EM structure of the SAGA and NuA4 coactivator subunit Tra1 at 3.7 angstrom resolutionSimultaneous inhibition of ATR and PARP sensitizes colon cancer cell lines to irinotecan.Interactions Between Ataxia Telangiectasia Mutated Kinase Inhibition, Poly(ADP-ribose) Polymerase-1 Inhibition and BRCA1 Status in Breast Cancer Cells.Downregulation of PARP1 transcription by CDK4/6 inhibitors sensitizes human lung cancer cells to anticancer drug-induced death by impairing OGG1-dependent base excision repair.14-3-3σ Contributes to Radioresistance By Regulating DNA Repair and Cell Cycle via PARP1 and CHK2.Role of novel histone modifications in cancer.Recruitment of ubiquitin-activating enzyme UBA1 to DNA by poly(ADP-ribose) promotes ATR signalling
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Visualization of a DNA-PK/PARP1 complex.
@en
type
label
Visualization of a DNA-PK/PARP1 complex.
@en
prefLabel
Visualization of a DNA-PK/PARP1 complex.
@en
P2860
P50
P356
P1476
Visualization of a DNA-PK/PARP1 complex
@en
P2093
Edward P Morris
Jody Barbeau
P2860
P304
P356
10.1093/NAR/GKR1231
P577
2012-01-05T00:00:00Z