Targeting SRC and epidermal growth factor receptor in colorectal cancer: rationale and progress into the clinic.
about
The SRC family of protein tyrosine kinases: a new and promising target for colorectal cancer therapy.Slit2/Robo1 signaling promotes intestinal tumorigenesis through Src-mediated activation of the Wnt/β-catenin pathway.Dasatinib, a Src inhibitor, sensitizes liver metastatic colorectal carcinoma to oxaliplatin in tumors with high levels of phospho-Src.The activation of G protein-coupled estrogen receptor induces relaxation via cAMP as well as potentiates contraction via EGFR transactivation in porcine coronary arteries.Natural compound Oblongifolin C confers gemcitabine resistance in pancreatic cancer by downregulating Src/MAPK/ERK pathways.Novel β-phenylacrylic acid derivatives exert anti-cancer activity by inducing Src-mediated apoptosis in wild-type KRAS colon cancer
P2860
Targeting SRC and epidermal growth factor receptor in colorectal cancer: rationale and progress into the clinic.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Targeting SRC and epidermal gr ...... and progress into the clinic.
@en
type
label
Targeting SRC and epidermal gr ...... and progress into the clinic.
@en
prefLabel
Targeting SRC and epidermal gr ...... and progress into the clinic.
@en
P2860
P1476
Targeting SRC and epidermal gr ...... e and progress into the clinic
@en
P2093
Scott Kopetz
P2860
P304
P433
P577
2007-01-01T00:00:00Z