Hot-spot consensus of fluoroquinolone-mediated DNA cleavage by Gram-negative and Gram-positive type II DNA topoisomerases.
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Molecular and Pharmacologic Properties of the Anticancer Quinolone Derivative Vosaroxin: A New Therapeutic Agent for Acute Myeloid LeukemiaVoreloxin is an anticancer quinolone derivative that intercalates DNA and poisons topoisomerase IITargeting acute myeloid leukemia with TP53-independent vosaroxin.Homologous recombination repair is essential for repair of vosaroxin-induced DNA double-strand breaks.Insights into the mechanism of inhibition of novel bacterial topoisomerase inhibitors from characterization of resistant mutants of Staphylococcus aureus.Gemifloxacin, a fluoroquinolone antimicrobial drug, inhibits migration and invasion of human colon cancer cellsFunctional determinants of gate-DNA selection and cleavage by bacterial type II topoisomerases.Clerocidin selectively modifies the gyrase-DNA gate to induce irreversible and reversible DNA damage.Iron(III)-binding of the anticancer agents doxorubicin and vosaroxin.
P2860
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P2860
Hot-spot consensus of fluoroquinolone-mediated DNA cleavage by Gram-negative and Gram-positive type II DNA topoisomerases.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Hot-spot consensus of fluoroqu ...... ve type II DNA topoisomerases.
@en
type
label
Hot-spot consensus of fluoroqu ...... ve type II DNA topoisomerases.
@en
prefLabel
Hot-spot consensus of fluoroqu ...... ve type II DNA topoisomerases.
@en
P2093
P2860
P50
P356
P1476
Hot-spot consensus of fluoroqu ...... ve type II DNA topoisomerases.
@en
P2093
Elisabetta Leo
Giulia Giaretta
L Mark Fisher
Lesley A Mitchenall
Valentina Comuzzi
P2860
P304
P356
10.1093/NAR/GKM653
P577
2007-08-30T00:00:00Z