The omega-3 polyunsaturated fatty acid DHA induces simultaneous apoptosis and autophagy via mitochondrial ROS-mediated Akt-mTOR signaling in prostate cancer cells expressing mutant p53
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Docosahexaenoic Acid Induces Oxidative DNA Damage and Apoptosis, and Enhances the Chemosensitivity of Cancer CellsOmega-3 Fatty Acids and Cancer Cell Cytotoxicity: Implications for Multi-Targeted Cancer TherapyInvolvement of apoptotic pathways in docosahexaenoic acid-induced benefit in prostate cancer: Pathway-focused gene expression analysis using RT2 Profile PCR Array System.The omega-3 polyunsaturated fatty acid docosahexaenoic acid inhibits proliferation and progression of non-small cell lung cancer cells through the reactive oxygen species-mediated inactivation of the PI3K /Akt pathwayOmega-3 free fatty acids suppress macrophage inflammasome activation by inhibiting NF-κB activation and enhancing autophagyInhibition of Autophagy Promotes Salinomycin-Induced Apoptosis via Reactive Oxygen Species-Mediated PI3K/AKT/mTOR and ERK/p38 MAPK-Dependent Signaling in Human Prostate Cancer Cells.Docosahexaenoic acid-induced apoptosis is mediated by activation of mitogen-activated protein kinases in human cancer cellsCoenzyme Q10 inhibits the aging of mesenchymal stem cells induced by D-galactose through Akt/mTOR signalingDifferential Ratios of Omega Fatty Acids (AA/EPA+DHA) Modulate Growth, Lipid Peroxidation and Expression of Tumor Regulatory MARBPs in Breast Cancer Cell Lines MCF7 and MDA-MB-231Surface chemistry but not aspect ratio mediates the biological toxicity of gold nanorods in vitro and in vivo.The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cellsKrill oil extract suppresses cell growth and induces apoptosis of human colorectal cancer cells.Omega-3 Polyunsaturated Fatty Acids May Attenuate Streptozotocin-Induced Pancreatic β-Cell Death via Autophagy Activation in Fat1 Transgenic Mice.Nifuroxazide exerts potent anti-tumor and anti-metastasis activity in melanomaDocosahexaenoic acid suppresses breast cancer cell metastasis by targeting matrix-metalloproteinases.Breaking the cycle: the role of omega-3 polyunsaturated fatty acids in inflammation-driven cancers.Negative regulation of the inflammasome: keeping inflammation under control.Omega-3 polyunsaturated fatty acids and cancer: lessons learned from clinical trials.Integrative metabolomics as emerging tool to study autophagy regulation.Metabolic and molecular regulation of dietary polyunsaturated fatty acids on prostate cancer.Fish-Derived Omega-3 Fatty Acids and Prostate Cancer: A Systematic Review.The unfolded protein response in the therapeutic effect of hydroxy-DHA against Alzheimer's disease.ER stress and impaired autophagy flux in neuronal degeneration and brain injury.Docosahexanoic acid antagonizes TNF-α-induced necroptosis by attenuating oxidative stress, ceramide production, lysosomal dysfunction, and autophagic featuresAssociation of cancer metabolism-related proteins with oral carcinogenesis - indications for chemoprevention and metabolic sensitizing of oral squamous cell carcinoma?AKT/mTOR and c-Jun N-terminal kinase signaling pathways are required for chrysotile asbestos-induced autophagy.n-3 Fatty acids modulate the mRNA expression of the Nlrp3 inflammasome and Mtor in the liver of rats fed with high-fat or high-fat/fructose diets.Docosahexaenoic Acid Induces Cell Death in Human Non-Small Cell Lung Cancer Cells by Repressing mTOR via AMPK Activation and PI3K/Akt Inhibition.The lauric acid-activated signaling prompts apoptosis in cancer cells.Platinum-Based Drugs Differentially Affect the Ultrastructure of Breast Cancer Cell Types.Iron oxide magnetic nanoparticles combined with actein suppress non-small-cell lung cancer growth in a p53-dependent manner.Lipid Extracts from the Brains of Silver Carp (Hypophthalmichthys molitrix) Induce Apoptosis in MCF-7 Cells through the Generation of Reactive Oxygen Species and the Mitochondrial Pathway.ω-hydroxyundec-9-enoic acid induces apoptosis by ROS mediated JNK and p38 phosphorylation in breast cancer cell lines.High Endogenous Accumulation of ω-3 Polyunsaturated Fatty Acids Protect against Ischemia-Reperfusion Renal Injury through AMPK-Mediated Autophagy in Fat-1 Mice.Omega-3 docosahexaenoic acid induces pyroptosis cell death in triple-negative breast cancer cells.Documentation of Ultrastructural Changes in Nucleus and Microvilli by Fish Oil in Experimental Colon Carcinogenesis.Docosahexaenoic Acid Attenuated Experimental Chronic Colitis in Interleukin 10-Deficient Mice by Enhancing Autophagy Through Inhibition of the mTOR Pathway.Attenuation of choroidal neovascularization by dietary intake of ω-3 long-chain polyunsaturated fatty acids and lutein in mice.
P2860
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P2860
The omega-3 polyunsaturated fatty acid DHA induces simultaneous apoptosis and autophagy via mitochondrial ROS-mediated Akt-mTOR signaling in prostate cancer cells expressing mutant p53
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
The omega-3 polyunsaturated fa ...... er cells expressing mutant p53
@en
type
label
The omega-3 polyunsaturated fa ...... er cells expressing mutant p53
@en
prefLabel
The omega-3 polyunsaturated fa ...... er cells expressing mutant p53
@en
P2093
P2860
P356
P1476
The omega-3 polyunsaturated fa ...... er cells expressing mutant p53
@en
P2093
Byung-Doo Hwang
Gi-Ryang Kweon
Ji-Hoon Park
Jong-Il Park
Kaipeng Jing
Kang-Sik Seo
Kyoung-Sub Song
Nayeong Kim
Seung-Kiel Park
P2860
P304
P356
10.1155/2013/568671
P407
P577
2013-06-10T00:00:00Z