Longitudinal genome-wide analysis of patients with chronic lymphocytic leukemia reveals complex evolution of clonal architecture at disease progression and at the time of relapse.
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Deciphering the molecular landscape in chronic lymphocytic leukemia: time frame of disease evolutionThe biology and clinical significance of acquired genomic copy number aberrations and recurrent gene mutations in chronic lymphocytic leukemiaMonoclonal B-cell lymphocytosis and early-stage chronic lymphocytic leukemia: diagnosis, natural history, and risk stratificationGenomic and epigenomic heterogeneity in chronic lymphocytic leukemiaGenomic characterization of high-count MBL cases indicates that early detection of driver mutations and subclonal expansion are predictors of adverse clinical outcome.Deep sequencing identifies genetic heterogeneity and recurrent convergent evolution in chronic lymphocytic leukemia.Monoclonal B-cell lymphocytosis is characterized by mutations in CLL putative driver genes and clonal heterogeneity many years before disease progression.Genetic and epigenetic profiling of CLL disease progression reveals limited somatic evolution and suggests a relationship to memory-cell developmentA Quantitative Analysis of Subclonal and Clonal Gene Mutations before and after Therapy in Chronic Lymphocytic Leukemia.Detection of chromothripsis-like patterns with a custom array platform for chronic lymphocytic leukemia.Longitudinal copy number, whole exome and targeted deep sequencing of 'good risk' IGHV-mutated CLL patients with progressive diseaseClonal evolution, genomic drivers, and effects of therapy in chronic lymphocytic leukemiaThe Dohner fluorescence in situ hybridization prognostic classification of chronic lymphocytic leukaemia (CLL): the CLL Research Consortium experienceClinical application of targeted and genome-wide technologies: can we predict treatment responses in chronic lymphocytic leukemia?Genetic subclonal complexity and miR125a-5p down-regulation identify a subset of patients with inferior outcome in low-risk CLL patients.Lessons from next-generation sequencing analysis in hematological malignancies.Evolving understanding of the CLL genome.Clonal evolution in chronic lymphocytic leukemia: impact of subclonality on disease progression.Chronic lymphocytic leukemia: Time to go past genomics?Waldenstrom Macroglobulinemia: Genomic Aberrations and Treatment.Identification of recurrent truncated DDX3X mutations in chronic lymphocytic leukaemia.Hypodiploid multiple myeloma is characterized by more aggressive molecular markers than non-hyperdiploid multiple myeloma.
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P2860
Longitudinal genome-wide analysis of patients with chronic lymphocytic leukemia reveals complex evolution of clonal architecture at disease progression and at the time of relapse.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Longitudinal genome-wide analy ...... on and at the time of relapse.
@en
type
label
Longitudinal genome-wide analy ...... on and at the time of relapse.
@en
prefLabel
Longitudinal genome-wide analy ...... on and at the time of relapse.
@en
P2093
P2860
P356
P1433
P1476
Longitudinal genome-wide analy ...... ion and at the time of relapse
@en
P2093
D F Jelinek
D L Van Dyke
J E Eckel-Passow
R C Tschumper
P2860
P2888
P304
P356
10.1038/LEU.2012.14
P577
2012-01-20T00:00:00Z
P5875
P6179
1051203910