Quantitative contribution of CD4 and CD8 to T cell antigen receptor serial triggering
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Different Levels of T-Cell Receptor Triggering Induce Distinct Functions in Hepatitis B and Hepatitis C Virus-Specific Human CD4+ T-Cell ClonesAnalysis of successful immune responses in persons infected with hepatitis C virusCytokine-independent Jak3 activation upon T cell receptor (TCR) stimulation through direct association of Jak3 and the TCR complexLocalized populations of CD8 MHC class I tetramer SIV-specific T cells in lymphoid follicles and genital epitheliumSimian virus 40 large-T-antigen-specific rejection of mKSA tumor cells in BALB/c mice is critically dependent on both strictly tumor-associated, tumor-specific CD8(+) cytotoxic T lymphocytes and CD4(+) T helper cellsAntigen decoding by T lymphocytes: from synapses to fate determination.Decreased CD4 expression by polarized T helper 2 cells contributes to suboptimal TCR-induced phosphorylation and reduced Ca2+ signalingDifferential potency of regulatory T cell-mediated immunosuppression in kidney tumors compared to subcutaneous tumors.Selective accumulation of raft-associated membrane protein LAT in T cell receptor signaling assembliesMolecular requirements for T cell recognition by a major histocompatibility complex class II-restricted T cell receptor: the involvement of the fourth hypervariable loop of the Valpha domain.Potent T cell activation with dimeric peptide-major histocompatibility complex class II ligand: the role of CD4 coreceptor.Cross-reactivity of T cells and its role in the immune systemDouble-Negative αβ T Cells Are Early Responders to AKI and Are Found in Human KidneyCytomegalovirus vectors violate CD8+ T cell epitope recognition paradigms.CD8+ T cell immunodominance shifts during the early stages of acute LCMV infection independently from functional avidity maturationInterleukin-4-induced loss of CD8 expression and cytolytic function in effector CD8 T cells persists long term in vivo.The phenotype of type 1 and type 2 CD8+ T cells activated in vitro is affected by culture conditions and correlates with effector activity.Major histocompatibility complex class I-restricted alloreactive CD4+ T cells.CD4-independent T cells impair TCR triggering of CD4-dependent T cells: a putative mechanism for T cell affinity maturation.Developmental regulation of Lck targeting to the CD8 coreceptor controls signaling in naive and memory T cells.Antigen-specific signaling by a soluble, dimeric peptide/major histocompatibility complex class II/Fc chimera leading to T helper cell type 2 differentiation.An abrupt and concordant initiation of apoptosis: antigen-dependent death of CD8+ CTL.Two intermediate-avidity cytotoxic T lymphocyte clones with a disparity between functional avidity and MHC tetramer staining.Perturbation of naive TCR transgenic T cell functional responses and upstream activation events by anti-CD4 monoclonal antibodies.Quantitative events determine the differentiation and function of helper T cells.Long-term proliferation and survival of in vitro-activated T cells is dependent on Interleukin-2 receptor signalling but not on the high-affinity IL-2R.A mathematical analysis of TCR serial triggering and down-regulation.Different T Cell Receptor Affinity Thresholds and CD8 Coreceptor Dependence Govern Cytotoxic T Lymphocyte Activation and Tetramer Binding Properties
P2860
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P2860
Quantitative contribution of CD4 and CD8 to T cell antigen receptor serial triggering
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Quantitative contribution of CD4 and CD8 to T cell antigen receptor serial triggering
@en
type
label
Quantitative contribution of CD4 and CD8 to T cell antigen receptor serial triggering
@en
prefLabel
Quantitative contribution of CD4 and CD8 to T cell antigen receptor serial triggering
@en
P2093
P2860
P356
P1476
Quantitative contribution of CD4 and CD8 to T cell antigen receptor serial triggering
@en
P2093
P2860
P304
P356
10.1084/JEM.186.10.1775
P407
P577
1997-11-01T00:00:00Z