In-depth qualitative and quantitative analysis of composite glycosylation profiles and other micro-heterogeneity on intact monoclonal antibodies by high-resolution native mass spectrometry using a modified Orbitrap
about
The diverse and expanding role of mass spectrometry in structural and molecular biologyGlycan analysis of therapeutic glycoproteinsOpening the door to innovationOptimal Synthetic Glycosylation of a Therapeutic AntibodyOptimal Synthetic Glycosylation of a Therapeutic AntibodyPepsin-Containing Membranes for Controlled Monoclonal Antibody Digestion Prior to Mass Spectrometry Analysis.Resolving the micro-heterogeneity and structural integrity of monoclonal antibodies by hybrid mass spectrometric approachesRapid quantitative analysis of monoclonal antibody heavy and light chain charge heterogeneityDirect analysis of aberrant glycosylation on haptoglobin in patients with gastric cancer.Boundaries of mass resolution in native mass spectrometry.Exposing the subunit diversity and modularity of protein complexes by structural mass spectrometry approaches.Bioanalytical approaches for characterizing catabolism of antibody-drug conjugates.Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates.Qualitative and quantitative characterization of protein biotherapeutics with liquid chromatography mass spectrometry.Native Mass Spectrometry: What is in the Name?Defining the stoichiometry and cargo load of viral and bacterial nanoparticles by Orbitrap mass spectrometryGlobal N-Glycan Site Occupancy of HIV-1 gp120 by Metabolic Engineering and High-Resolution Intact Mass Spectrometry.Precise quantification of mixtures of bispecific IgG produced in single host cells by liquid chromatography-Orbitrap high-resolution mass spectrometry.Antibody-drug conjugate model fast characterization by LC-MS following IdeS proteolytic digestion.Application of the Exactive Plus EMR for automated protein-ligand screening by non-covalent mass spectrometry.Serum glycosylation characterization of osteonecrosis of the femoral head by mass spectrometry.Advances in native high-performance liquid chromatography and intact mass spectrometry for the characterization of biopharmaceutical products.Characterization of a Porous Nano-electrospray Capillary Emitter at Ultra-low Flow Rates.Antibody-drug conjugates: present and future.Comprehensive Proteoform Characterization of Plasma Complement Component C8αβγ by Hybrid Mass Spectrometry Approaches.Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S.Simultaneous assessment of kinetic, site-specific, and structural aspects of enzymatic protein phosphorylation.Native mass spectrometry combined with enzymatic dissection unravels glycoform heterogeneity of biopharmaceuticals.Use of a charge reducing agent to enable intact mass analysis of cysteine-linked antibody-drug-conjugates by native mass spectrometry.Detailed mass analysis of structural heterogeneity in monoclonal antibodies using native mass spectrometryN-glycan microheterogeneity regulates interactions of plasma proteins
P2860
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P2860
In-depth qualitative and quantitative analysis of composite glycosylation profiles and other micro-heterogeneity on intact monoclonal antibodies by high-resolution native mass spectrometry using a modified Orbitrap
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
In-depth qualitative and quant ...... etry using a modified Orbitrap
@en
type
label
In-depth qualitative and quant ...... etry using a modified Orbitrap
@en
prefLabel
In-depth qualitative and quant ...... etry using a modified Orbitrap
@en
P2093
P2860
P356
P1476
In-depth qualitative and quant ...... etry using a modified Orbitrap
@en
P2093
Ewald T J van den Bremer
Janine Schuurman
Johannis P Kamerling
Sara Rosati
P2860
P304
P356
10.4161/MABS.26282
P577
2013-08-28T00:00:00Z