The exonuclease activity of DNA polymerase γ is required for ligation during mitochondrial DNA replication. - Wikidata - wikimedia - TriplyDB

The exonuclease activity of DNA polymerase γ is required for ligation during mitochondrial DNA replication.

The exonuclease activity of DNA polymerase γ is required for ligation during mitochondrial DNA replication.

http://www.wikidata.org/entity/Q41883034

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Pathogenicity in POLG syndromes: DNA polymerase gamma pathogenicity prediction server and database.MGME1 processes flaps into ligatable nicks in concert with DNA polymerase γ during mtDNA replication.Nucleotide pools dictate the identity and frequency of ribonucleotide incorporation in mitochondrial DNA.Complementation between polymerase- and exonuclease-deficient mitochondrial DNA polymerase mutants in genomically engineered flies.Mitochondrial transcription termination factor 1 directs polar replication fork pausing.Regulation of DNA replication at the end of the mitochondrial D-loop involves the helicase TWINKLE and a conserved sequence element.A multi-systemic mitochondrial disorder due to a dominant p.Y955H disease variant in DNA polymerase gamma.Synergistic Effects of the in cis T251I and P587L Mitochondrial DNA Polymerase γ Disease Mutations.Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria.The mitochondrial DNA polymerase gamma degrades linear DNA fragments precluding the formation of deletions.Mitochondrial DNA replication in mammalian cells: overview of the pathway Calorie restriction does not influence oocyte quality in oocytes from POLG mitochondrial mutator mice A two-nuclease pathway involving RNase H1 is required for primer removal at human mitochondrial OriL Structural insights into DNA degradation by human mitochondrial nuclease MGME1

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The exonuclease activity of DNA polymerase γ is required for ligation during mitochondrial DNA replication.

http://www.wikidata.org/entity/Q41883034

description

2015 nî lūn-bûn

@nan

2015年の論文

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2015年論文

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2015年論文

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2015年論文

@zh-hk

2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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name

The exonuclease activity of DN ...... mitochondrial DNA replication.

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The exonuclease activity of DN ...... mitochondrial DNA replication.

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The exonuclease activity of DN ...... mitochondrial DNA replication.

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Nature Communications

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The exonuclease activity of DN ...... mitochondrial DNA replication

@en

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Bertil Macao

http://www.w3.org/2001/XMLSchema#string

Claes M Gustafsson

http://www.w3.org/2001/XMLSchema#string

Maria Falkenberg

http://www.w3.org/2001/XMLSchema#string

Monica Olsson

http://www.w3.org/2001/XMLSchema#string

Triinu Siibak

http://www.w3.org/2001/XMLSchema#string

Wenwen Sheng

http://www.w3.org/2001/XMLSchema#string

Xuefeng Zhu

http://www.w3.org/2001/XMLSchema#string

Yonghong Shi

http://www.w3.org/2001/XMLSchema#string

P2860

The human DNA ligase III gene encodes nuclear and mitochondrial proteins

Premature ageing in mice expressing defective mitochondrial DNA polymerase

Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease

Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates

Human Dna2 is a nuclear and mitochondrial DNA maintenance protein

Idling by DNA polymerase delta maintains a ligatable nick during lagging-strand DNA replication

Reconstitution of a minimal mtDNA replisome in vitro

DNA sequence analysis with a modified bacteriophage T7 DNA polymerase

The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability

Mitochondrial DNA replication and disease: insights from DNA polymerase γ mutations

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7303

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scholarly article

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10.1038/NCOMMS8303

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6

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James Bruce Stewart

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2015-06-22T00:00:00Z

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278963288

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26095671

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mitochondrial DNA

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4557304

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