Comparison of HDAC inhibitors in clinical development: effect on HIV production in latently infected cells and T-cell activation.
about
Targeting the latent reservoir to achieve functional HIV cureEpigenetic control of HIV-1 post integration latency: implications for therapyImpact of Chromatin on HIV ReplicationManipulation of the host protein acetylation network by human immunodeficiency virus type 1Rational development of radiopharmaceuticals for HIV-1Multi-dose Romidepsin Reactivates Replication Competent SIV in Post-antiretroviral Rhesus Macaque ControllersTIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV InfectionHistone deacetylase inhibitors impair the elimination of HIV-infected cells by cytotoxic T-lymphocytesTargeting the Brain Reservoirs: Toward an HIV CureHistone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing.An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patientsActivation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapySynergistic Reactivation of Latent HIV Expression by Ingenol-3-Angelate, PEP005, Targeted NF-kB Signaling in Combination with JQ1 Induced p-TEFb ActivationEpigenetic Control of Human Endogenous Retrovirus Expression: Focus on Regulation of Long-Terminal Repeats (LTRs)A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes.The CCR5-antagonist Maraviroc reverses HIV-1 latency in vitro alone or in combination with the PKC-agonist Bryostatin-1High-throughput Characterization of HIV-1 Reservoir Reactivation Using a Single-Cell-in-Droplet PCR Assay.Late-emerging strains of HIV induce T-cell homeostasis failure by promoting bystander cell death and immune exhaustion in naïve CD4 and all CD8 T-cells.The microRNA miR-29a is associated with human immunodeficiency virus latency.Exploring the potential of monoclonal antibody therapeutics for HIV-1 eradication.Progress toward curing HIV infections with hematopoietic stem cell transplantation.Specific inhibition of histone deacetylase 8 reduces gene expression and production of proinflammatory cytokines in vitro and in vivoHIV-1 transcriptional regulation in the central nervous system and implications for HIV cure researchAutophagy induction by histone deacetylase inhibitors inhibits HIV type 1.Dynamics of HIV latency and reactivation in a primary CD4+ T cell model.Ex vivo response to histone deacetylase (HDAC) inhibitors of the HIV long terminal repeat (LTR) derived from HIV-infected patients on antiretroviral therapy.Eradication of HIV-1 from the macrophage reservoir: an uncertain goal?Genome editing strategies: potential tools for eradicating HIV-1/AIDS.The Depsipeptide Romidepsin Reverses HIV-1 Latency In VivoTargeting Histone Deacetylases in Diseases: Where Are We?Reactivation of Latent HIV-1 Expression by Engineered TALE Transcription Factors.Ex Vivo Bioactivity and HIV-1 Latency Reversal by Ingenol Dibenzoate and Panobinostat in Resting CD4(+) T Cells from Aviremic Patients.Euphorbia Kansui Reactivates Latent HIV.Synergistic Activation of Latent HIV-1 Expression by Novel Histone Deacetylase Inhibitors and Bryostatin-1.Molecular mechanisms of HIV latency.In Vitro Reactivation of Replication-Competent and Infectious HIV-1 by Histone Deacetylase Inhibitors.Sequential treatment with 5-aza-2'-deoxycytidine and deacetylase inhibitors reactivates HIV-1.Small Molecule Inhibitors of BAF; A Promising Family of Compounds in HIV-1 Latency ReversalHuman endogenous retrovirus (HERV) expression is not induced by treatment with the histone deacetylase (HDAC) inhibitors in cellular models of HIV-1 latencyDevelopment of 5' LTR DNA methylation of latent HIV-1 provirus in cell line models and in long-term-infected individuals
P2860
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P2860
Comparison of HDAC inhibitors in clinical development: effect on HIV production in latently infected cells and T-cell activation.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Comparison of HDAC inhibitors ...... d cells and T-cell activation.
@en
type
label
Comparison of HDAC inhibitors ...... d cells and T-cell activation.
@en
prefLabel
Comparison of HDAC inhibitors ...... d cells and T-cell activation.
@en
P2860
P50
P356
P1476
Comparison of HDAC inhibitors ...... d cells and T-cell activation.
@en
P2093
Christel Brinkmann
Jesper Melchjorsen
P2860
P304
P356
10.4161/HV.23800
P50
P577
2013-01-31T00:00:00Z