The copper binding domain of SPARC mediates cell survival in vitro via interaction with integrin beta1 and activation of integrin-linked kinase.
about
Matricellular proteins: a sticky affair with cancersMatrikine and matricellular regulators of EGF receptor signaling on cancer cell migration and invasionSPARC Promotes Cell Invasion In Vivo by Decreasing Type IV Collagen Levels in the Basement MembranemiR-8 modulates cytoskeletal regulators to influence cell survival and epithelial organization in Drosophila wings.Lack of host SPARC enhances vascular function and tumor spread in an orthotopic murine model of pancreatic carcinoma.Roles of Copper-Binding Proteins in Breast Cancer.Processing of the matricellular protein hevin in mouse brain is dependent on ADAMTS4KLF4 inhibition of lung cancer cell invasion by suppression of SPARC expression.PTEN augments SPARC suppression of proliferation and inhibits SPARC-induced migration by suppressing SHC-RAF-ERK and AKT signaling.SPARC mediates metastatic cooperation between CSC and non-CSC prostate cancer cell subpopulations.A role for SPARC in the moderation of human insulin secretionControl of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARCRevisiting the matricellular concept.SPARC promotes pericyte recruitment via inhibition of endoglin-dependent TGF-β1 activity.Retinal glia promote dorsal root ganglion axon regeneration.The delayed recovery of the remobilized rat tibialis anterior muscle reflects a defect in proliferative and terminal differentiation that impairs early regenerative processesDeletion of the SPARC acidic domain or EGF-like module reduces SPARC-induced migration and signaling through p38 MAPK/HSP27 in glioma.SPARC Controls Melanoma Cell Plasticity through Rac1.Age-related resistance of skeletal muscle-derived progenitor cells to SPARC may explain a shift from myogenesis to adipogenesis.Integrin β4 regulates SPARC protein to promote invasion.Cellular and molecular mechanisms of renal fibrosis.Echistatin prevents posterior capsule opacification in diabetic rabbit model via integrin linked kinase signaling pathwayThe Function of SPARC as a Mediator of Fibrosis.SPARC triggers a cell-autonomous program of synapse eliminationEffects of lentiviral RNA interference-mediated downregulation of integrin-linked kinase on biological behaviors of human lens epithelial cells.PTEN suppresses SPARC-induced pMAPKAPK2 and inhibits SPARC-induced Ser78 HSP27 phosphorylation in gliomaSPARC accelerates disease progression in experimental crescentic glomerulonephritisRole of p38MAPK and oxidative stress in copper-induced senescence.A holistic approach to dissecting SPARC family protein complexity reveals FSTL-1 as an inhibitor of pancreatic cancer cell growth.SPARC: a matricellular regulator of tumorigenesis.SPARC promotes leukemic cell growth and predicts acute myeloid leukemia outcome.Integrin-linked kinase 1: role in hormonal cancer progression.The regulatory function of SPARC in vascular biology.Diverse biological functions of the SPARC family of proteins.Biomarkers for predicting future metastasis of human gastrointestinal tumors.Stromal expression of SPARC in pancreatic adenocarcinoma.Astrocyte-secreted matricellular proteins in CNS remodelling during development and diseaseMolecular mechanisms underlying the divergent roles of SPARC in human carcinogenesis.Copper as a key regulator of cell signalling pathways.The Effects of Acute and Chronic Exercise on Skeletal Muscle Proteome.
P2860
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P2860
The copper binding domain of SPARC mediates cell survival in vitro via interaction with integrin beta1 and activation of integrin-linked kinase.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The copper binding domain of S ...... ion of integrin-linked kinase.
@en
type
label
The copper binding domain of S ...... ion of integrin-linked kinase.
@en
prefLabel
The copper binding domain of S ...... ion of integrin-linked kinase.
@en
P2093
P2860
P356
P1476
The copper binding domain of S ...... ion of integrin-linked kinase.
@en
P2093
E Helene Sage
Gail Workman
Matt S Weaver
P2860
P304
22826-22837
P356
10.1074/JBC.M706563200
P407
P577
2008-05-23T00:00:00Z