The C. elegans homolog of the mammalian tumor suppressor Dep-1/Scc1 inhibits EGFR signaling to regulate binary cell fate decisions.
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Phosphatome profiling reveals PTPN2, PTPRJ and PTEN as potent negative regulators of PKB/Akt activation in Ras-mutated cancer cellsNew role for the protein tyrosine phosphatase DEP-1 in Akt activation and endothelial cell survivalAn unbiased screen identifies DEP-1 tumor suppressor as a phosphatase controlling EGFR endocytosisCell fate-specific regulation of EGF receptor trafficking during Caenorhabditis elegans vulval developmentProtein tyrosine phosphatases expression during development of mouse superior colliculusSystemic Regulation of RAS/MAPK Signaling by the Serotonin Metabolite 5-HIAAAn AGEF-1/Arf GTPase/AP-1 ensemble antagonizes LET-23 EGFR basolateral localization and signaling during C. elegans vulva inductionA Drosophila-centric view of protein tyrosine phosphatasesRas effector switching promotes divergent cell fates in C. elegans vulval patterning.Predictive modeling of signaling crosstalk during C. elegans vulval development.Simulation-based model checking approach to cell fate specification during Caenorhabditis elegans vulval development by hybrid functional Petri net with extension.The Caenorhabditis elegans CDT-2 ubiquitin ligase is required for attenuation of EGFR signalling in vulva precursor cells.Cancer models in Caenorhabditis elegans.RAB-7 antagonizes LET-23 EGFR signaling during vulva development in Caenorhabditis elegansLogic programming to predict cell fate patterns and retrodict genotypes in organogenesis.Robustness and evolution: concepts, insights and challenges from a developmental model system.The tyrosine phosphatase PTPRO sensitizes colon cancer cells to anti-EGFR therapy through activation of SRC-mediated EGFR signalingThe epidermal growth factor receptor family: biology driving targeted therapeutics.Executing multicellular differentiation: quantitative predictive modelling of C.elegans vulval development.Zebrafish grainyhead-like1 is a common marker of different non-keratinocyte epidermal cell lineages, which segregate from each other in a Foxi3-dependent mannerβ-Integrin de-phosphorylation by the Density-Enhanced Phosphatase DEP-1 attenuates EGFR signaling in C. elegans.Phosphotyrosine phosphatase R3 receptors: Origin, evolution and structural diversificationSEL-10/Fbw7-dependent negative feedback regulation of LIN-45/Braf signaling in C. elegans via a conserved phosphodegron.Protein-tyrosine phosphatases and cancer.Interactions between Type III receptor tyrosine phosphatases and growth factor receptor tyrosine kinases regulate tracheal tube formation in Drosophila.Morphogenesis of the caenorhabditis elegans vulva.Receptor tyrosine phosphatases control tracheal tube geometries through negative regulation of Egfr signaling.R3 receptor tyrosine phosphatases: conserved regulators of receptor tyrosine kinase signaling and tubular organ development.C. elegans Vulva Induction: An In Vivo Model to Study Epidermal Growth Factor Receptor Signaling and Trafficking.The protein tyrosine phosphatase DEP-1/PTPRJ promotes breast cancer cell invasion and metastasis.Protein-tyrosine phosphatase DEP-1 controls receptor tyrosine kinase FLT3 signaling.Hybrid Modeling of Cell Signaling and Transcriptional Reprogramming and Its Application in C. elegans Development.Ras effector switching as a developmental strategy.A novel splice variant of the protein tyrosine phosphatase PTPRJ that encodes for a soluble protein involved in angiogenesis.A Real-Time Biosensor for ERK Activity Reveals Signaling Dynamics during C. elegans Cell Fate Specification.The receptor protein tyrosine phosphatase PTPRJ negatively modulates the CD98hc oncoprotein in lung cancer cells.
P2860
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P2860
The C. elegans homolog of the mammalian tumor suppressor Dep-1/Scc1 inhibits EGFR signaling to regulate binary cell fate decisions.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
The C. elegans homolog of the ...... te binary cell fate decisions.
@en
type
label
The C. elegans homolog of the ...... te binary cell fate decisions.
@en
prefLabel
The C. elegans homolog of the ...... te binary cell fate decisions.
@en
P2860
P356
P1433
P1476
The C. elegans homolog of the ...... te binary cell fate decisions.
@en
P2093
Alex Hajnal
Thomas A Berset
P2860
P304
P356
10.1101/GAD.333505
P577
2005-05-18T00:00:00Z