Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation. - Wikidata - wikimedia - TriplyDB

Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation.

Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation.

http://www.wikidata.org/entity/Q41893585

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Decreased plasma levels of soluble CD18 link leukocyte infiltration with disease activity in spondyloarthritis Apilimod inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis Heparanase is preferentially expressed in human psoriatic lesions and induces development of psoriasiform skin inflammation in mice.Plasmin plays an essential role in amplification of psoriasiform skin inflammation in mice Auf1/Hnrnpd-deficient mice develop pruritic inflammatory skin disease.Sun exposure rapidly reduces plasmacytoid dendritic cells and inflammatory dermal dendritic cells in psoriatic skin.Tumor progression locus 2 (Tpl2) kinase promotes chemokine receptor expression and macrophage migration during acute inflammation.Mannan induces ROS-regulated, IL-17A-dependent psoriasis arthritis-like disease in mice.CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host disease.Complement modulates the cutaneous microbiome and inflammatory milieu.Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth Neutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice Depletion of antigen-presenting cells by clodronate liposomes reverses the psoriatic skin phenotype in KC-Tie2 mice.Multiple helminth infection of the skin causes lymphocyte hypo-responsiveness mediated by Th2 conditioning of dermal myeloid cells.Misbehaving macrophages in the pathogenesis of psoriasis.Bone marrow stromal cells as immunomodulators. A primer for dermatologists.Topical application of delphinidin reduces psoriasiform lesions in the flaky skin mouse model by inducing epidermal differentiation and inhibiting inflammation Depletion of cutaneous macrophages and dendritic cells promotes growth of basal cell carcinoma in mice.Colony-stimulating factor-1 promotes kidney growth and repair via alteration of macrophage responses.An eosinophil immune response characterizes the inflammatory skin disease observed in Tie-2 transgenic mice.Role of TNF-α in virus-induced airway hyperresponsiveness and neuronal M₂ muscarinic receptor dysfunction.T cell-extrinsic CD18 attenuates antigen-dependent CD4+ T cell activation in vivo.NF-κB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis Quantitative expansion of ES cell-derived myeloid progenitors capable of differentiating into macrophages.Critical involvement of macrophage infiltration in the development of Sjögren's syndrome-associated dry eye.Outer surface protein OspC is an antiphagocytic factor that protects Borrelia burgdorferi from phagocytosis by macrophages.Update on psoriasis immunopathogenesis and targeted immunotherapy.The evaluation of psoriasis therapy with biologics leads to a revision of the current view of the pathogenesis of this disorder.Psoriasis: evolution of pathogenic concepts and new therapies through phases of translational research.Sunlight triggers cutaneous lupus through a CSF-1-dependent mechanism in MRL-Fas(lpr) mice.Cardiometabolic risk in psoriasis: differential effects of biologic agents.Cytokines are systemic effectors of lymphatic function in acute inflammation Induction of IL-17+ T cell trafficking and development by IFN-gamma: mechanism and pathological relevance in psoriasis.Alternatively activated macrophage-derived RELM-{alpha} is a negative regulator of type 2 inflammation in the lung.Upregulation of ANGPTL6 in mouse keratinocytes enhances susceptibility to psoriasis.Genome-wide association scan yields new insights into the immunopathogenesis of psoriasis.Psoriasis: from pathogenesis to novel therapeutic approaches.Innate immunity in the pathogenesis of psoriasis.Mononuclear phagocyte system in kidney disease and repair.Chemokine receptors in psoriasis.

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P2860

Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation.

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Activated macrophages are esse ...... soriasiform skin inflammation.

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Anca Sindrilaru

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Andreas C Renkl

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Athanasios Stratis

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Cord Sunderkötter

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Daniel Kess

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Honglin Wang

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Ingo Haase

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Nico Van Rooijen

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Thorsten Peters

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Tsvetelina Oreshkova

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P2860

Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis

Integrins: a family of cell surface receptors

Gene for familial psoriasis susceptibility mapped to the distal end of human chromosome 17q

The immunologic and genetic basis of psoriasis.

Interleukin-11 therapy selectively downregulates type I cytokine proinflammatory pathways in psoriasis lesions.

Characterization of lymphocyte-dependent angiogenesis using a SCID mouse: human skin model of psoriasis.

Synergistic activity of interleukin-4 and interleukin-10 in suppression of inflammation and joint destruction in rheumatoid arthritis.

Anti-TNF-alpha therapies: the next generation.

Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities.

Psoriasis of the scalp. Diagnosis and management.

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2105-2114

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10.1172/JCI27180

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116

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6900865

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