Elimination of C/EBPalpha through the ubiquitin-proteasome system promotes the development of liver cancer in mice.
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Epigenetic changes play critical role in age-associated dysfunctions of the liver.Cooperation of C/EBP family proteins and chromatin remodeling proteins is essential for termination of liver regenerationThe oncoprotein p28GANK establishes a positive feedback loop in β-catenin signaling.Intracellular signaling and hepatocellular carcinoma.The reduction of SIRT1 in livers of old mice leads to impaired body homeostasis and to inhibition of liver proliferation.Effects on polo-like kinase 1 polo-box domain binding affinities of peptides incurred by structural variation at the phosphoamino acid position.Transcriptional and translational regulation of C/EBPβ-HDAC1 protein complexes controls different levels of p53, SIRT1, and PGC1α proteins at the early and late stages of liver cancer.SAG-UPS attenuates proapoptotic SARM and Noxa to confer survival advantage to early hepatocellular carcinoma.Age-associated change of C/EBP family proteins causes severe liver injury and acceleration of liver proliferation after CCl4 treatments.Gankyrin sustains PI3K/GSK-3β/β-catenin signal activation and promotes colorectal cancer aggressiveness and progression.The role of CUGBP1 in age-dependent changes of liver functions.Gankyrin regulates cell signaling network.FXR-Gankyrin axis is involved in development of pediatric liver cancer.Farnesoid X receptor inhibits gankyrin in mouse livers and prevents development of liver cancer.The hypoxia-inducible factor-C/EBPα axis controls ethanol-mediated hepcidin repression.A tumor suppressor role for C/EBPα in solid tumors: more than fat and blood.Increased expression of enzymes of triglyceride synthesis is essential for the development of hepatic steatosisp300 Regulates Liver Functions by Controlling p53 and C/EBP Family Proteins through Multiple Signaling Pathways.Upregulation of PSMD10 caused by the JMJD2A histone demethylase.The oncoprotein gankyrin promotes the development of colitis-associated cancer through activation of STAT3.RB and p53 cooperate to prevent liver tumorigenesis in response to tissue damage.Ghrelin deletion protects against age-associated hepatic steatosis by downregulating the C/EBPα-p300/DGAT1 pathway.Tumour promotion versus tumour suppression in chronic hepatic iron overload.RNA Binding Protein CUGBP1 Inhibits Liver Cancer in a Phosphorylation-Dependent Manner.Activation of CDK4 Triggers Development of Non-alcoholic Fatty Liver Disease.Arctigenin Inhibits Liver Cancer Tumorigenesis by Inhibiting Gankyrin Expression via C/EBPα and PPARα.PARP1 activation increases expression of modified tumor suppressors and pathways underlying development of aggressive hepatoblastoma
P2860
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P2860
Elimination of C/EBPalpha through the ubiquitin-proteasome system promotes the development of liver cancer in mice.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Elimination of C/EBPalpha thro ...... pment of liver cancer in mice.
@en
type
label
Elimination of C/EBPalpha thro ...... pment of liver cancer in mice.
@en
prefLabel
Elimination of C/EBPalpha thro ...... pment of liver cancer in mice.
@en
P2093
P2860
P356
P1476
Elimination of C/EBPalpha thro ...... pment of liver cancer in mice.
@en
P2093
Angela Major
Guo-Li Wang
Jingling Jin
Milton Finegold
Nikolai A Timchenko
Polina Iakova
Simon Haefliger
Xiurong Shi
P2860
P304
P356
10.1172/JCI41933
P407
P577
2010-07-01T00:00:00Z