The APC gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer.
about
Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc geneRole of the Wnt/β-catenin pathway in gastric cancer: An in-depth literature reviewPhysical localisation of the breakpoints of a constitutional translocation t(5;6)(q21;q21) in a child with bilateral Wilms' tumour.Alterations of tumor suppressor and tumor-related genes in the development and progression of gastric cancerPathogenetic mechanisms in gastric cancer.In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infectionAn insight into the genetic pathway of adenocarcinoma of the small intestineAPC mutations in sporadic medulloblastomas.Somatic mutations of the APC gene in primary breast cancers.Inverse relationship between APC gene mutation in gastric adenomas and development of adenocarcinoma.Detection of a Tumor Suppressor Gene Variant Predisposing to Colorectal Cancer in an 18th Century Hungarian Mummy.Chromosome 5 allelic losses are early events in tumours of the papilla of Vater and occur at sites similar to those of gastric cancerGenomic evolution in Barrett's adenocarcinoma cells: critical roles of elevated hsRAD51, homologous recombination and Alu sequences in the genome.Loss of heterozygosity on chromosome 5q in ovarian cancer is frequently accompanied by TP53 mutation and identifies a tumour suppressor gene locus at 5q13.1-21.Allelic imbalance on chromosome 5q predicts long-term survival in neuroblastomaMutation analysis of APC gene in gastric cancer with microsatellite instability.Upregulated expression of DIXDC1 in intestinal-type gastric carcinoma: co-localization with β-catenin and correlation with poor prognosisTwo additional potential retrotransposons isolated from a human L1 subfamily that contains an active retrotransposable element.Chromosome band 16q24 is frequently deleted in human gastric cancerSensitive and specific detection of early gastric cancer with DNA methylation analysis of gastric washes.Gastric cancer and related epigenetic alterations.PolyDoms: a whole genome database for the identification of non-synonymous coding SNPs with the potential to impact disease.Epigenetic regulation of APC in the molecular pathogenesis of gallbladder cancerGastric Carcinogenesis and Underlying Molecular Mechanisms: Helicobacter pylori and Novel Targeted Therapy.Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formationDeletion mapping on chromosome 1p in well-differentiated gastric cancer.Molecular biology and gastric carcinoma.Reconstructed beta-catenin/TCF4 signaling in yeast applicable to functional evaluation of APC mutations.The genomics of lung adenocarcinoma: opportunities for targeted therapies.Allelotype analysis of adenocarcinoma of the gastric cardia.Abnormal expression and function of the E-cadherin-catenin complex in gastric carcinoma cell lines.Gene mutations in stool from gastric and colorectal neoplasia patients by next-generation sequencing.Gene mutations in stool from gastric and colorectal neoplasia patients by next-generation sequencing.Wnt/β‑catenin pathway activation and silencing of the APC gene in HPV‑positive human cervical cancer‑derived cells.Primary gastric carcinoma cells frequently lose heterozygosity at the APC and MCC genetic loci.State of adenomatous polyposis coli gene and ras oncogenes in Japanese prostate cancer.Analysis of the beta-catenin/T cell factor signaling pathway in 36 gastrointestinal and liver cancer cells.The effects of sodium chloride, miso or ethanol on development of intestinal metaplasia after X-irradiation of the rat glandular stomach.Recombination and its roles in DNA repair, cellular immortalization and cancer
P2860
Q24562061-41722E55-47E9-450F-9A2F-630C1D2B91DBQ28086989-448FBAC1-F2BC-477C-A2F8-5BA5DA600F9DQ33678730-7BD75E84-911C-4C2D-AA68-08974A902127Q33788100-58B7C24F-C697-42CA-B15E-54E358881716Q34326627-04AFCB7D-5C2D-4F46-B45E-EF0412637846Q34758575-A5F57145-A96A-4F3C-A648-2E2972B04E1FQ35594366-CDB1FB8E-F875-47A7-B497-60C5A27F001FQ35745470-E335BBD8-DF36-4BD4-88FC-76847361BF80Q35745531-CF641BF1-A473-46D9-B3AE-2A4F9CCF0202Q35747605-FBA93F6D-9748-463C-AE35-36E1E34BAE58Q35919764-5770E69A-2BBB-4F74-A639-1F94CCFF6381Q36115845-A2D1A5F0-BA73-4C30-B950-759C0DFECF80Q36120783-7F0A839E-78EC-4480-B9AD-7E7FB9FBFB4BQ36135600-438523F4-B8DD-4EF3-B833-7AC4EEF5B291Q36136428-CC732E94-A9FA-442C-986F-6ED1B36731C3Q36308958-A2DD5045-CAA9-455E-BFED-76B0EBD3F7A0Q36383885-F7C8D465-4713-4758-87E5-6DD5559CC59BQ36416853-017351FC-3AC4-42AF-8664-FF84712B7D86Q36617849-8DBDB2D9-5770-45B9-8EBD-EA45870C97B6Q37294995-94E97536-136C-4825-8797-D56E009AB0E4Q37592416-265393BB-D0EF-4F45-A678-FD8D4328B39BQ38517226-8765FF7E-3D24-4BBD-947B-6C3B9A338AAEQ38810882-97402C33-70AA-4FE1-8DC1-2997EED675E0Q39838743-8EE3E85B-3773-4583-9791-9D321306604EQ39969056-30E2101B-7B55-436E-9E0E-555F23DAF453Q39993827-F572F97B-C612-49A0-9EAA-13FE956AEC31Q40875518-CE37E33B-2138-4866-811A-9B0945FD63F2Q41815356-594312A2-BD9E-4BD4-AA45-218D70B324C6Q41891513-8553D3A3-590E-4615-A6D0-2D4B5DFCFF5FQ41931838-034BAB96-C325-4366-8A29-29220894462BQ42015210-C3DA738D-D93A-41C7-9BC2-85F7A4F39FFCQ47106128-3C6B3C82-C974-4C92-936E-C535F7D0D095Q47200284-6FF63E2D-692D-4EFE-8958-714A46E972ADQ47587176-9146DCA7-A198-417F-9A21-5518ADDA8D78Q53477859-CD7793A0-6AAE-48E0-ADB1-95E6AF9C33D0Q54198813-3F003A6D-1B5A-4547-9AF5-C2419B1E15CFQ54534218-BDF74848-F46F-4C81-9DE5-6148AA074D32Q55040243-8E695BD2-8BD9-4A49-B6F2-3D32DA114E02Q56902268-B18CDF3D-B4EF-426B-BE56-5E751D78D98A
P2860
The APC gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
The APC gene, responsible for ...... tated in human gastric cancer.
@en
type
label
The APC gene, responsible for ...... tated in human gastric cancer.
@en
prefLabel
The APC gene, responsible for ...... tated in human gastric cancer.
@en
P2093
P1433
P1476
The APC gene, responsible for ...... tated in human gastric cancer.
@en
P2093
Nakamura Y
Nakatsuru S
Yanagisawa A
P304
P407
P577
1992-06-01T00:00:00Z