WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells. - Wikidata - wikimedia - TriplyDB

WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells.

WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells.

http://www.wikidata.org/entity/Q41897453

about

Wiskott-Aldrich syndrome protein controls antigen-presenting cell-driven CD4+ T-cell motility by regulating adhesion to intercellular adhesion molecule-1 Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity Human Immunodeficiencies Related to Defective APC/T Cell Interaction Milk: an exosomal microRNA transmitter promoting thymic regulatory T cell maturation preventing the development of atopy?T-regulatory cells in primary immune deficiencies Regulatory T cells in transplantation Actin cytoskeletal defects in immunodeficiency Unbalanced Immune System: Immunodeficiencies and Autoimmunity Inflammatory bowel disease Autoimmunity in primary T-cell immunodeficiencies.FOXP3+ Tregs require WASP to restrain Th2-mediated food allergy CD28-CD80 interactions control regulatory T cell motility and immunological synapse formation.In Vivo Chronic Stimulation Unveils Autoreactive Potential of Wiskott-Aldrich Syndrome Protein-Deficient B Cells.Systemic lupus erythematosus and Wiskott-Aldrich syndrome in an Italian patient.Hematopoietic cell transplantation for Wiskott-Aldrich syndrome: advances in biology and future directions for treatment.Wiskott-Aldrich syndrome: a comprehensive review.Current and emerging treatment options for Wiskott-Aldrich syndrome.Age-Dependent Defects of Regulatory B Cells in Wiskott-Aldrich Syndrome Gene Knockout Mice N-WASP is required for B-cell-mediated autoimmunity in Wiskott-Aldrich syndrome.Wiskott-Aldrich syndrome protein is required for homeostasis and function of invariant NKT cells.Critical requirement for the Wiskott-Aldrich syndrome protein in Th2 effector function.Colitis and colon cancer in WASP-deficient mice require helicobacter species.Systemic autoimmunity and defective Fas ligand secretion in the absence of the Wiskott-Aldrich syndrome protein Nuclear role of WASp in gene transcription is uncoupled from its ARP2/3-dependent cytoplasmic role in actin polymerization.Genes and environment: how will our concepts on the pathophysiology of IBD develop in the future?Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome.Exacerbated experimental arthritis in Wiskott-Aldrich syndrome protein deficiency: modulatory role of regulatory B cells Itk: the rheostat of the T cell response.Defective inhibition of B-cell proliferation by Wiskott-Aldrich syndrome protein-deficient regulatory T cells Intestinal alkaline phosphatase has beneficial effects in mouse models of chronic colitis WASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunity.The Wiskott-Aldrich syndrome protein permits assembly of a focused immunological synapse enabling sustained T-cell receptor signaling.Mechanisms of allergic disease - environmental and genetic determinants for the development of allergy.Harnessing regulatory T cells for the treatment of inflammatory bowel disease.Gene/cell therapy approaches for Immune Dysregulation Polyendocrinopathy Enteropathy X-linked syndrome.B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice.Dendritic cell functional improvement in a preclinical model of lentiviral-mediated gene therapy for Wiskott-Aldrich syndrome Autoimmunity in wiskott-Aldrich syndrome: an unsolved enigma.Lymphocyte-dependent and Th2 cytokine-associated colitis in mice deficient in Wiskott-Aldrich syndrome protein.Lentiviral-mediated gene therapy restores B cell tolerance in Wiskott-Aldrich syndrome patients.

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P2860

WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells.

http://www.wikidata.org/entity/Q41897453

description

2007 nî lūn-bûn

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

WASP regulates suppressor acti ...... +) natural regulatory T cells.

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type

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WASP regulates suppressor acti ...... +) natural regulatory T cells.

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WASP regulates suppressor acti ...... +) natural regulatory T cells.

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Journal of Experimental Medicine

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WASP regulates suppressor acti ...... +) natural regulatory T cells.

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P2093

Alessandro Aiuti

http://www.w3.org/2001/XMLSchema#string

Anna Villa

http://www.w3.org/2001/XMLSchema#string

Ayse Metin

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Cristina Panaroni

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Federica Cattaneo

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Francesco Marangoni

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Loïc Dupré

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Luigi D Notarangelo

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Maria-Grazia Roncarolo

http://www.w3.org/2001/XMLSchema#string

Samantha Scaramuzza

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P2860

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires

A function for interleukin 2 in Foxp3-expressing regulatory T cells

Activation by Cdc42 and PIP(2) of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complex

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

Spontaneous apoptosis in lymphocytes from patients with Wiskott-Aldrich syndrome: correlation of accelerated cell death and attenuated bcl-2 expression.

P304

369-380

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10.1084/JEM.20061334

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2

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204

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Manuela Battaglia

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2007-02-12T00:00:00Z

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6508134

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2118740

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