Cortisol is transported by the multidrug resistance gene product P-glycoprotein. - Wikidata - wikimedia - TriplyDB

Cortisol is transported by the multidrug resistance gene product P-glycoprotein.

Cortisol is transported by the multidrug resistance gene product P-glycoprotein.

http://www.wikidata.org/entity/Q41901794

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Appropriate function of 11beta-hydroxysteroid dehydrogenase type 1 in the endoplasmic reticulum lumen is dependent on its N-terminal region sharing similar topological determinants with 50-kDa esterase The ATP binding cassette transporters Pdr5 and Snq2 of Saccharomyces cerevisiae can mediate transport of steroids in vivo Major vault protein LRP-related multidrug resistance Cmdr1, a chicken P-glycoprotein, confers multidrug resistance and interacts with estradiol.Development and function of the human fetal adrenal cortex: a key component in the feto-placental unit.Pharmacogenetics and pharmacogenomics in rheumatology.LEM1, an ATP-binding-cassette transporter, selectively modulates the biological potency of steroid hormones.The E23 early gene of Drosophila encodes an ecdysone-inducible ATP-binding cassette transporter capable of repressing ecdysone-mediated gene activation.Multidrug-resistance gene 1-type p-glycoprotein (MDR1 p-gp) inhibition by tariquidar impacts on neuroendocrine and behavioral processing of stress.Progress in defining multidrug resistance in leukemia.Interactions between antidepressants and P-glycoprotein at the blood-brain barrier: clinical significance of in vitro and in vivo findings.Systemic inflammation-associated glucocorticoid resistance and outcome of ARDS.Localization of breast cancer resistance protein (Bcrp) in endocrine organs and inhibition of its transport activity by steroid hormones.Cerebrospinal fluid cortisol and progesterone profiles and outcomes prognostication after severe traumatic brain injury.Pulmonary co-infection with Nocardia and Aspergillus in a patient with adult-onset Still's disease receiving steroids and tacrolimus Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.Circumvention of chemotherapy-induced myelosuppression by transfer of the mdr1 gene.Assessment of systemic toxicity in children receiving chemotherapy with cyclosporine for sarcoma.Glucocorticoid resistance in childhood leukemia.Dexamethasone-resistant human Pre-B leukemia 697 cell line evolving elevation of intracellular glutathione level: an additional resistance mechanism.Role of multidrug resistance P-glycoprotein in the secretion of aldosterone by human adrenal NCI-H295 cells.Drug resistance, illustration of the complexity of translational research. Steiner Award lecture 1995.Dexverapamil to modulate vinblastine resistance in metastatic renal cell carcinoma.Multidrug resistance in cancer chemotherapy.Addition of etoposide to initial therapy of adult acute lymphoblastic leukemia: a combined clinical and laboratory study.Thyroid hormone export regulates cellular hormone content and response.An FK506-sensitive transporter selectively decreases intracellular levels and potency of steroid hormones.Effects of steroids and verapamil on P-glycoprotein ATPase activity: progesterone, desoxycorticosterone, corticosterone and verapamil are mutually non-exclusive modulators.Changes in the brain accumulation of glucocorticoids in abcb1a-deficient CF-1 mice.In vivo model systems in P-glycoprotein-mediated multidrug resistance.Structure-activity relationships for xenobiotic transport substrates and inhibitory ligands of P-glycoprotein.Relevance of p-glycoprotein for the enteral absorption of cyclosporin A: in vitro-in vivo correlation Increased sensitivity to gemcitabine of P-glycoprotein and multidrug resistance-associated protein-overexpressing human cancer cell lines.Effects of the ABCB1 (1199G > A) Polymorphism on Steroid Sex Hormone-Induced P-Glycoprotein Expression, ATPase Activity, and Hormone Efflux.Administration of drugs known to inhibit P-glycoprotein increases brain bilirubin and alters the regional distribution of bilirubin in rat brain.Response to glucocorticoids and toxicity in childhood acute lymphoblastic leukemia: role of polymorphisms of genes involved in glucocorticoid response.Behavioural consequences of p-glycoprotein deficiency in mice, with special focus on stress-related mechanisms.Effects of antidepressants on the brain/plasma distribution of corticosterone.Different transport activity of human triallelic MDR1 893Ala/Ser/Thr variant and its association with herb extracts.Immunohistochemical detection of P-glycoprotein in teleost tissues using mammalian polyclonal and monoclonal antibodies.

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P2860

Cortisol is transported by the multidrug resistance gene product P-glycoprotein.

http://www.wikidata.org/entity/Q41901794

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1993 nî lūn-bûn

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Cortisol is transported by the multidrug resistance gene product P-glycoprotein.

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Cortisol is transported by the multidrug resistance gene product P-glycoprotein.

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Cortisol is transported by the multidrug resistance gene product P-glycoprotein.

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British Journal of Cancer

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Cortisol is transported by the multidrug resistance gene product P-glycoprotein.

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Broxterman HJ

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Dekker H

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Feller N

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Lankelma J

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Pinedo HM

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van Kalken CK

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P2860

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

Expression of a multidrug-resistance gene in human tumors and tissues

Cyclosporin A and verapamil have different effects on energy metabolism in multidrug-resistant tumour cells.

The outward transport of cortisol by mammalian cells in vitro.

The biochemistry of P-glycoprotein-mediated multidrug resistance.

Resistance to multiple chemotherapeutic agents in human cancer cells.

Progesterone photoaffinity labels P-glycoprotein in multidrug-resistant human leukemic lymphoblasts.

Full length and alternatively spliced pgp1 transcripts in multidrug-resistant Chinese hamster lung cells.

P-glycoprotein drug efflux pump involved in the mechanisms of intrinsic drug resistance in various colon cancer cell lines. Evidence for a saturation of active daunorubicin transport.

Differential sensitivity of multi-drug-resistant and -sensitive cells to resistance-modifying agents and the relation with reversal of anthracycline resistance.

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284-289

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10.1038/BJC.1993.54

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2

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67

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Giuseppe Giaccone

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1993-02-01T00:00:00Z

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15105544

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1001443429

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8094292

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multiple drug resistance

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1968171

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