Simultaneous analysis of multiple monoclonal antibody biotherapeutics by LC-MS/MS method in rat plasma following cassette-dosing.
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Pepsin-Containing Membranes for Controlled Monoclonal Antibody Digestion Prior to Mass Spectrometry Analysis.Toward sensitive and accurate analysis of antibody biotherapeutics by liquid chromatography coupled with mass spectrometry.Time-Dependent Structural Alteration of Rituximab Analyzed by LC/TOF-MS after a Systemic Administration to Rats.Application and challenges in using LC-MS assays for absolute quantitative analysis of therapeutic proteins in drug discovery.The integration of ligand binding and LC-MS-based assays into bioanalytical strategies for protein analysis.Assessments of antibody biodistribution.Generic method approaches for monoclonal antibody therapeutics analysis using both ligand binding and LC-MS/MS techniques.Qualitative and quantitative characterization of protein biotherapeutics with liquid chromatography mass spectrometry.Quantification of XRCC and DNA-PK proteins in cancer cell lines and human tumors by LC-MS/MS.Automated DBS microsampling, microscale automation and microflow LC-MS for therapeutic protein PK.Absolute and multiplex quantification of antibodies in serum using PSAQ™ standards and LC-MS/MS.Recommendations for validation of LC-MS/MS bioanalytical methods for protein biotherapeutics.Quantitative LC/ESI-SRM/MS of antibody biopharmaceuticals: use of a homologous antibody as an internal standard and three-step method development.3-(4-Hydroxyphenyl)propionic acid: the forgotten detection substrate for ligand-binding assay-based bioanalysis.Reagent-free LC-MS/MS-based pharmacokinetic quantification of polyhistidine-tagged therapeutic proteins.Hybridizing LBA with LC-MS/MS: the new norm for biologics quantification.Orthogonal tools to help determine the required selectivity of ligand-binding assays in drug development.
P2860
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P2860
Simultaneous analysis of multiple monoclonal antibody biotherapeutics by LC-MS/MS method in rat plasma following cassette-dosing.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Simultaneous analysis of multi ...... sma following cassette-dosing.
@en
type
label
Simultaneous analysis of multi ...... sma following cassette-dosing.
@en
prefLabel
Simultaneous analysis of multi ...... sma following cassette-dosing.
@en
P2093
P2860
P1433
P1476
Simultaneous analysis of multi ...... sma following cassette-dosing.
@en
P2093
Christopher A James
Hongyan Li
Hossein Salimi-Moosavi
Jean W Lee
Jennifer Malella
Linh T B Tran
Robert Ortiz
P2860
P2888
P304
P356
10.1208/S12248-012-9435-5
P407
P577
2012-12-12T00:00:00Z
P5875
P6179
1000477979