Antizyme, a protein induced by polyamines, accelerates the degradation of ornithine decarboxylase in Chinese-hamster ovary-cell extracts.
about
Structural elements of antizymes 1 and 2 are required for proteasomal degradation of ornithine decarboxylaseA unified pathway for the degradation of ornithine decarboxylase in reticulocyte lysate requires interaction with the polyamine-induced protein, ornithine decarboxylase antizymegutfeeling, a Drosophila gene encoding an antizyme-like protein, is required for late differentiation of neurons and musclesATP-Dependent inactivation and sequestration of ornithine decarboxylase by the 26S proteasome are prerequisites for degradationPleiotropic defects caused by loss of the proteasome-interacting factors Rad23 and Rpn10 of Saccharomyces cerevisiae.Yeast ornithine decarboxylase and antizyme form a 1:1 complex in vitro: purification and characterization of the inhibitory complexPolyamines regulate the expression of ornithine decarboxylase antizyme in vitro by inducing ribosomal frame-shifting.Antizyme protects against abnormal accumulation and toxicity of polyamines in ornithine decarboxylase-overproducing cellsPlacing a disrupted degradation motif at the C terminus of proteasome substrates attenuates degradation without impairing ubiquitylation.Polyamine transport by mammalian cells and mitochondria: role of antizyme and glycosaminoglycans.Proteasomes of the yeast S. cerevisiae: genes, structure and functions.Degradation of antizyme inhibitor, an ornithine decarboxylase homologous protein, is ubiquitin-dependent and is inhibited by antizyme.Rapid and regulated degradation of ornithine decarboxylase.Regulated degradation of the transcription factor Gcn4.Polyamine regulation of ornithine decarboxylase and its antizyme in intestinal epithelial cells.Two zebrafish (Danio rerio) antizymes with different expression and activitiesAnti-tumor activity of antizyme which targets the ornithine decarboxylase (ODC) required for cell growth and transformation.Translational bypassing: a new reading alternative of the genetic code.Degradation of the 74 kDa form of L-histidine decarboxylase via the ubiquitin-proteasome pathway in a rat basophilic/mast cell line (RBL-2H3).Feedback repression of ornithine decarboxylase synthesis mediated by antizyme.Overproduction of stable ornithine decarboxylase and antizyme in the difluoromethylornithine-resistant cell line DH23b.Regulation of mammalian ornithine decarboxylase. Studies on the induction of the enzyme by hypotonic stress.Forced expression of antizyme abolishes ornithine decarboxylase activity, suppresses cellular levels of polyamines and inhibits cell growth.On programmed ribosomal frameshifting: the alternative proteomes.Feedback regulation of mammalian ornithine decarboxylase. Studies using a transient expression system.Single amino-acid replacement is responsible for the stabilization of ornithine decarboxylase in HMOA cells.Multiple regulation of ornithine decarboxylase in enzyme-overproducing cells.Overexpression of antizyme in the hearts of transgenic mice prevents the isoprenaline-induced increase in cardiac ornithine decarboxylase activity and polyamines, but does not prevent cardiac hypertrophy.Osmotic stress induces variation in cellular levels of ornithine decarboxylase-antizyme.Degradation of ornithine decarboxylase: exposure of the C-terminal target by a polyamine-inducible inhibitory protein.Involvement of the proteasome and antizyme in ornithine decarboxylase degradation by a reticulocyte lysate.Distinct domains of antizyme required for binding and proteolysis of ornithine decarboxylase.Activation of rat brain ornithine decarboxylase by GTP.Identification of a region of p53 that confers lability.Ornithine decarboxylase activity during the development of Anastrepha fraterculus (Diptera, Tephritidae).The N terminus of antizyme promotes degradation of heterologous proteins.
P2860
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P2860
Antizyme, a protein induced by polyamines, accelerates the degradation of ornithine decarboxylase in Chinese-hamster ovary-cell extracts.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Antizyme, a protein induced by ...... e-hamster ovary-cell extracts.
@en
type
label
Antizyme, a protein induced by ...... e-hamster ovary-cell extracts.
@en
prefLabel
Antizyme, a protein induced by ...... e-hamster ovary-cell extracts.
@en
P2093
P2860
P356
P1433
P1476
Antizyme, a protein induced by ...... e-hamster ovary-cell extracts.
@en
P2093
P2860
P304
P356
10.1042/BJ2830661
P407
P478
283 ( Pt 3)
P577
1992-05-01T00:00:00Z