Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts.
about
Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patientsReversing T cell immunosenescence: why, who, and howPoly(A)-specific ribonuclease (PARN) mediates 3'-end maturation of the telomerase RNA componentInvestigation of human telomerase holoenzyme assembly, activity, and processivity using disease-linked subunit variants.The telomerase reverse transcriptase subunit from the dimorphic fungus Ustilago maydis.Telomere length in blood, buccal cells, and fibroblasts from patients with inherited bone marrow failure syndromesGenetic Variations in Telomere Maintenance, with Implications on Tissue Renewal Capacity and Chronic Disease Pathologies.DNA damage responses and oxidative stress in dyskeratosis congenita.Dyskeratosis congenita as a disorder of telomere maintenance.PCB153 reduces telomerase activity and telomere length in immortalized human skin keratinocytes (HaCaT) but not in human foreskin keratinocytes (NFK)Conditional Knockout of Telomerase Reverse Transcriptase in Mesenchymal Cells Impairs Mouse Pulmonary Fibrosis.Robust DNA Damage Response and Elevated Reactive Oxygen Species in TINF2-Mutated Dyskeratosis Congenita CellsDyskeratosis Congenita Dermal Fibroblasts are Defective in Supporting the Clonogenic Growth of Epidermal Keratinocytes.Characterization and rescue of telomeric abnormalities in ICF syndrome type I fibroblasts.Engineered telomere degradation models dyskeratosis congenitaThe role of telomeres in the ageing of human skin.Disease-associated human telomerase RNA variants show loss of function for telomere synthesis without dominant-negative interference.Recent insights into the molecular mechanisms involved in aging and the malignant transformation of adult stem/progenitor cells and their therapeutic implications.Three novel truncating TINF2 mutations causing severe dyskeratosis congenita in early childhoodPosttranscriptional manipulation of TERC reverses molecular hallmarks of telomere disease.Measuring relative telomere length: is tissue an issue?A novel TERC CR4/CR5 domain mutation causes telomere disease via decreased TERT binding.The p53/p21(WAF/CIP) pathway mediates oxidative stress and senescence in dyskeratosis congenita cells with telomerase insufficiency.
P2860
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P2860
Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Telomere restoration and exten ...... ratosis congenita fibroblasts.
@en
type
label
Telomere restoration and exten ...... ratosis congenita fibroblasts.
@en
prefLabel
Telomere restoration and exten ...... ratosis congenita fibroblasts.
@en
P2093
P2860
P1433
P1476
Telomere restoration and exten ...... eratosis congenita fibroblasts
@en
P2093
Elizabeth Chavez
Erik R Westin
Francoise A Gourronc
Frederick D Goldman
Kimberly M Lee
Peter M Lansdorp
Soraya Riley
P2860
P304
P356
10.1111/J.1474-9726.2007.00288.X
P577
2007-03-23T00:00:00Z