Triggered intracellular activation of disulfide crosslinked polyelectrolyte gene delivery complexes with extended systemic circulation in vivo. - Wikidata - wikimedia - TriplyDB

Triggered intracellular activation of disulfide crosslinked polyelectrolyte gene delivery complexes with extended systemic circulation in vivo.

Triggered intracellular activation of disulfide crosslinked polyelectrolyte gene delivery complexes with extended systemic circulation in vivo.

http://www.wikidata.org/entity/Q41919544

about

Enhanced gene and siRNA delivery by polycation-modified mesoporous silica nanoparticles loaded with chloroquine.pH-responsive polymeric sirna carriers sensitize multidrug resistant ovarian cancer cells to doxorubicin via knockdown of polo-like kinase 1.Dual-sensitive micellar nanoparticles regulate DNA unpacking and enhance gene-delivery efficiency.Decationized polyplexes as stable and safe carrier systems for improved biodistribution in systemic gene therapy Development of a novel endosomolytic diblock copolymer for siRNA delivery Bioreducible polycations in nucleic acid delivery: past, present, and future trends.Polyplex gene delivery modulated by redox potential gradients.Well-defined cross-linked antioxidant nanozymes for treatment of ischemic brain injury Matrices and scaffolds for DNA delivery in tissue engineering Synthetic delivery systems for intravenous administration of nucleic acids.Reducible poly(amido ethylenediamine) for hypoxia-inducible VEGF delivery.Polymers for DNA delivery.Novel biodegradable poly(disulfide amine)s for gene delivery with high efficiency and low cytotoxicity.Bioreducible hyperbranched poly(amido amine)s for gene delivery.Rational design of smart supramolecular assemblies for gene delivery: chemical challenges in the creation of artificial viruses.Polymeric Plerixafor: effect of PEGylation on CXCR4 antagonism, cancer cell invasion, and DNA transfection.Peptide-mediated RNA delivery: a novel approach for enhanced transfection of primary and post-mitotic cells.Bioreducible crosslinked polyelectrolyte complexes for MMP-2 siRNA delivery into human vascular smooth muscle cells.Biotinylated photocleavable polyethylenimine: capture and triggered release of nucleic acids from solid supports.Surface-engineered targeted PPI dendrimer for efficient intracellular and intratumoral siRNA delivery.Optical properties and application of a reactive and bioreducible thiol-containing tetramethylrhodamine dimer.Design and characterization of a new peptide vector for short interfering RNA delivery.Gene transfer with poly-melittin peptides.Vectors based on reducible polycations facilitate intracellular release of nucleic acids.Synthetic PEGylated glycoproteins and their utility in gene delivery.Polymeric redox-responsive delivery systems bearing ammonium salts cross-linked via disulfides.Design and engineering of disulfide crosslinked nanocomplexes of polyamide polyelectrolytes: stability under biorelevant conditions and potent cellular internalization of entrapped model peptide.Conjugate Polyplexes with Anti-Invasive Properties and Improved siRNA Delivery In Vivo.A mild and versatile approach for DNA encapsulation

P2860

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P2860

Triggered intracellular activation of disulfide crosslinked polyelectrolyte gene delivery complexes with extended systemic circulation in vivo.

http://www.wikidata.org/entity/Q41919544

description

2001 nî lūn-bûn

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2001年の論文

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2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

2001年论文

@zh

2001年论文

@zh-cn

name

Triggered intracellular activa ...... systemic circulation in vivo.

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type

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Triggered intracellular activa ...... systemic circulation in vivo.

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Triggered intracellular activa ...... systemic circulation in vivo.

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Triggered intracellular activa ...... systemic circulation in vivo.

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Carlisle RC

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Seymour LW

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P2860

Low molecular weight disulfide cross-linking peptides as nonviral gene delivery carriers.

PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery.

The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells.

Interactions of polymeric and liposomal gene delivery systems with extracellular glycosaminoglycans: physicochemical and transfection studies.

Putative role of chloroquine in gene transfer into a human hepatoma cell line by DNA/lactosylated polylysine complexes.

N-(2-hydroxypropyl)methacrylamide copolymers targeted to the hepatocyte galactose-receptor: pharmacokinetics in DBA2 mice.

The reduction of the positive charges of polylysine by partial gluconoylation increases the transfection efficiency of polylysine/DNA complexes.

Caged DNA does not aggregate in high ionic strength solutions.

A versatile system for receptor-mediated gene delivery permits increased entry of DNA into target cells, enhanced delivery to the nucleus and elevated rates of transgene expression.

Observation of DNA-polymer condensate formation in real time at a molecular level

P2888

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713-724

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scholarly article

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10.1038/SJ.GT.3301446

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9

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1015037001

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