Neuronal adaptation to amphetamine and dopamine: molecular mechanisms of prodynorphin gene regulation in rat striatum.
about
Protein kinase A-dependent derepression of the human prodynorphin gene via differential binding to an intragenic silencer element.Dynorphin, stress, and depressionKappa-opioid ligands in the study and treatment of mood disordersSex Differences in Kappa Opioid Receptor Function and Their Potential Impact on AddictionRole of kappa-opioid receptors in stress and anxiety-related behavior.Drug withdrawal conceptualized as a stressor.Molecular, cellular, and structural mechanisms of cocaine addiction: a key role for microRNAsMolecular mechanisms of synaptic remodeling in alcoholismPotassium chloride depolarization mediates CREB phosphorylation in striatal neurons in an NMDA receptor-dependent mannerAltered responsiveness to cocaine and increased immobility in the forced swim test associated with elevated cAMP response element-binding protein expression in nucleus accumbenscAMP response element-binding protein is required for dopamine-dependent gene expression in the intact but not the dopamine-denervated striatumStriatal signal transduction and drug addictionDopamine D(1) receptor-induced gene transcription is modulated by DARPP-32Chronic methamphetamine exposure suppresses the striatal expression of members of multiple families of immediate early genes (IEGs) in the rat: normalization by an acute methamphetamine injectionUnderstanding the neurobiological consequences of early exposure to psychotropic drugs: linking behavior with molecules.Molecular and genetic substrates linking stress and addictionTime-dependent effects of amphetamine on feeding in ratsRunning and cocaine both upregulate dynorphin mRNA in medial caudate putamen.Cyclic AMP and mitogen-activated protein kinases are required for glutamate-dependent cyclic AMP response element binding protein and Elk-1 phosphorylation in the dorsal striatum in vivo.Transient overexpression of alpha-Ca2+/calmodulin-dependent protein kinase II in the nucleus accumbens shell enhances behavioral responding to amphetamine.Dynorphin up-regulation in the dentate granule cell mossy fiber pathway following chronic inhibition of GluN2B-containing NMDAR is associated with increased CREB (Ser 133) phosphorylation, but is independent of BDNF/TrkB signaling pathwaysRegulation of neurotransmitter interactions in the ventral striatum.The Expanding Significance of Inositol Polyphosphate Multikinase as a Signaling Hub.Methamphetamine-induced stereotypy correlates negatively with patch-enhanced prodynorphin and arc mRNA expression in the rat caudate putamen: the role of mu opioid receptor activation.Depressive-like effects of the kappa opioid receptor agonist salvinorin A are associated with decreased phasic dopamine release in the nucleus accumbensCBP in the nucleus accumbens regulates cocaine-induced histone acetylation and is critical for cocaine-associated behaviors.Maladaptive striatal plasticity in L-DOPA-induced dyskinesia.Mitochondrial abnormalities in the putamen in Parkinson's disease dyskinesiaRegulation of gene expression and cocaine reward by CREB and DeltaFosB.Altered attention and prefrontal cortex gene expression in rats after binge-like exposure to cocaine during adolescenceDopamine D1 receptors mediate CREB phosphorylation via phosphorylation of the NMDA receptor at Ser897-NR1.Molecular components of striatal plasticity: the various routes of cyclic AMP pathways.Dopamine-dependent increases in phosphorylation of cAMP response element binding protein (CREB) during precipitated morphine withdrawal in primary cultures of rat striatum.Cocaine and the AP-1 transcription factor complex.Activation of CREB in the nucleus accumbens shell produces anhedonia and resistance to extinction of fear in rats.Pathobiology of dynorphins in trauma and disease.Inhibitory role of inducible cAMP early repressor (ICER) in methamphetamine-induced locomotor sensitization.The Role of BDNF/TrkB Signaling in Acute Amphetamine-Induced Locomotor Activity and Opioid Peptide Gene Expression in the Rat Dorsal Striatum.κ Opioid receptors in the nucleus accumbens shell mediate escalation of methamphetamine intake.Repeated exposure to the κ-opioid receptor agonist salvinorin A modulates extracellular signal-regulated kinase and reward sensitivity.
P2860
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P2860
Neuronal adaptation to amphetamine and dopamine: molecular mechanisms of prodynorphin gene regulation in rat striatum.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Neuronal adaptation to ampheta ...... ne regulation in rat striatum.
@en
type
label
Neuronal adaptation to ampheta ...... ne regulation in rat striatum.
@en
prefLabel
Neuronal adaptation to ampheta ...... ne regulation in rat striatum.
@en
P2093
P2860
P1433
P1476
Neuronal adaptation to ampheta ...... ne regulation in rat striatum.
@en
P2093
P2860
P304
P356
10.1016/0896-6273(95)90225-2
P407
P577
1995-04-01T00:00:00Z