Hedgehog-targeted therapeutics uncouple the vicious cycle of bone metastasis.

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The Role of Sonic Hedgehog Signaling in Osteoclastogenesis and Jaw Bone Destruction.The Role of Prolactin in Bone Metastasis and Breast Cancer Cell-Mediated Osteoclast Differentiation.

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Hedgehog-targeted therapeutics uncouple the vicious cycle of bone metastasis.

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2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

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2012年論文

@zh-tw

2012年论文

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2012年论文

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2012年论文

@zh-cn

name

Hedgehog-targeted therapeutics uncouple the vicious cycle of bone metastasis.

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type

Item

label

Hedgehog-targeted therapeutics uncouple the vicious cycle of bone metastasis.

@en

prefLabel

Hedgehog-targeted therapeutics uncouple the vicious cycle of bone metastasis.

@en

P1476

Hedgehog-targeted therapeutics uncouple the vicious cycle of bone metastasis.

@en

P2093

Katherine N Weilbaecher

http://www.w3.org/2001/XMLSchema#string

Michelle A Hurchla

http://www.w3.org/2001/XMLSchema#string

P2860

Targeting Hedgehog--a cancer stem cell pathway

Hedgehog pathway as a drug target: Smoothened inhibitors in development.

Vismodegib.

Osteoblast-secreted collagen upregulates paracrine Sonic hedgehog signaling by prostate cancer cells and enhances osteoblast differentiation.

Hedgehog signaling inhibition blocks growth of resistant tumors through effects on tumor microenvironment.

Cancer to bone: a fatal attraction.

Paracrine Hedgehog signaling in cancer.

Prostate cancer cells and bone stromal cells mutually interact with each other through bone morphogenetic protein-mediated signals.

The hedgehog signaling molecule Gli2 induces parathyroid hormone-related peptide expression and osteolysis in metastatic human breast cancer cells.

The hedgehog pathway conditions the bone microenvironment for osteolytic metastasis of breast cancer.

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1411-1413

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scholarly article

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10.4161/ONCI.21060

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P478

http://www.w3.org/2001/XMLSchema#string

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2012-11-01T00:00:00Z

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P5875

233932008

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P698

23243611

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P932

3518520

http://www.w3.org/2001/XMLSchema#string

Hedgehog-targeted therapeutics uncouple the vicious cycle of bone metastasis.

about

P2860

P2860

Hedgehog-targeted therapeutics uncouple the vicious cycle of bone metastasis.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P5875

P698

P932