Chloroquine modulation of specific metabolizing enzymes activities: investigation with selective five drug cocktail.
about
Development of a new generation of 4-aminoquinoline antimalarial compounds using predictive pharmacokinetic and toxicology models.Summary of information on human CYP enzymes: human P450 metabolism data.Interactions of herbs with cytochrome P450.The conduct of in vitro and in vivo drug-drug interaction studies: a PhRMA perspective.How useful is the "cocktail approach" for evaluating human hepatic drug metabolizing capacity using cytochrome P450 phenotyping probes in vivo?Lead optimization of antimalarial propafenone analogues."Cocktail" approaches and strategies in drug development: valuable tool or flawed science?Pharmacokinetic and pharmacodynamic assessment of a five-probe metabolic cocktail for CYPs 1A2, 3A4, 2C9, 2D6 and 2E1.Influence of hydroxychloroquine on the bioavailability of oral metoprololTherapy and pharmacological properties of hydroxychloroquine and chloroquine in treatment of systemic lupus erythematosus, rheumatoid arthritis and related diseases.Evaluation of the drug interaction potential of aplaviroc, a novel human immunodeficiency virus entry inhibitor, using a modified cooperstown 5 + 1 cocktail.Characterisation of artemisinin-chloroquinoline hybrids for potential metabolic liabilities.A convenient five-drug cocktail for the assessment of major drug metabolizing enzymes: a pilot study.The effects of Panax notoginseng saponins (PNS) on the activities of 'rat' CYP2C9, CYP2D6 and CYP3A4.In Vivo and In Vitro Activities and ADME-Tox Profile of a Quinolizidine-Modified 4-Aminoquinoline: A Potent Anti-P. falciparum and Anti-P. vivax Blood-Stage Antimalarial.Artemisinin antimalarials moderately affect cytochrome P450 enzyme activity in healthy subjects.Evaluation on activity of cytochrome p450 enzymes in turbot via a probe drug cocktail.
P2860
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P2860
Chloroquine modulation of specific metabolizing enzymes activities: investigation with selective five drug cocktail.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Chloroquine modulation of spec ...... selective five drug cocktail.
@en
type
label
Chloroquine modulation of spec ...... selective five drug cocktail.
@en
prefLabel
Chloroquine modulation of spec ...... selective five drug cocktail.
@en
P2093
P2860
P1476
Chloroquine modulation of spec ...... selective five drug cocktail.
@en
P2093
P2860
P304
P356
10.1046/J.1365-2125.1998.00765.X
P407
P577
1998-09-01T00:00:00Z