The molecular structure and lubricating activity of lubricin isolated from bovine and human synovial fluids.
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The secreted glycoprotein lubricin protects cartilage surfaces and inhibits synovial cell overgrowthCadherin-11 induces rheumatoid arthritis fibroblast-like synoviocytes to form lining layers in vitroHyaluronan and synovial joint: function, distribution and healingThe effect of the carbohydrate moiety upon the size and conformation of human plasma galactoglycoprotein as judged by electron microscopy and circular dichroism. Structural studies of a glycoprotein after stepwise enzymic carbohydrate removalTemporomandibular joint formation and condyle growth require Indian hedgehog signalingMultimodal evaluation of tissue-engineered cartilage.Homology of lubricin and superficial zone protein (SZP): products of megakaryocyte stimulating factor (MSF) gene expression by human synovial fibroblasts and articular chondrocytes localized to chromosome 1q25.Study on the lubrication mechanism of natural joints by confocal laser scanning microscopy.The impact of anterior cruciate ligament injury on lubricin metabolism and the effect of inhibiting tumor necrosis factor alpha on chondroprotection in an animal model.Microscale frictional response of bovine articular cartilage from atomic force microscopy.Cartilage interstitial fluid load support in unconfined compression.Hydrostatic pressurization and depletion of trapped lubricant pool during creep contact of a rippled indenter against a biphasic articular cartilage layer.Distribution of lubricin in the ruptured human rotator cuff and biceps tendon: a pilot studySynergistic Interactions of a Synthetic Lubricin-Mimetic with Fibronectin for Enhanced Wear Protection.Boundary lubrication in vivo.Lubricin is Required for the Structural Integrity and Post-natal Maintenance of TMJ.BMPRIA mediated signaling is essential for temporomandibular joint development in mice.Loss of cartilage structure, stiffness, and frictional properties in mice lacking PRG4.Extracorporeal shockwave-induced expression of lubricin in tendons and septa.Consequences of disease-causing mutations on lubricin protein synthesis, secretion, and post-translational processing.Novel mutations in PRG4 gene in two Indian families with camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome.Effects of supplemental intra-articular lubricin and hyaluronic acid on the progression of posttraumatic arthritis in the anterior cruciate ligament-deficient rat knee.Rheopexy of synovial fluid and protein aggregationMapping lubricin in canine musculoskeletal tissues.Anti-lubricin monoclonal antibodies created using lubricin-knockout mice immunodetect lubricin in several species and in patients with healthy and diseased joints.Elastoviscous Transitions of Articular Cartilage Reveal a Mechanism of Synergy between Lubricin and Hyaluronic Acid.Cartilage boundary lubrication synergism is mediated by hyaluronan concentration and PRG4 concentration and structure.Unmasking Heavily O-Glycosylated Serum Proteins Using Perchloric Acid: Identification of Serum Proteoglycan 4 and Protease C1 Inhibitor as Molecular Indicators for Screening of Breast Cancer.Binding and lubrication of biomimetic boundary lubricants on articular cartilage.Effects of equine joint injury on boundary lubrication of articular cartilage by synovial fluid: role of hyaluronan.Mechanisms of synovial joint and articular cartilage formation: recent advances, but many lingering mysteries.Human synovial lubricin expresses sialyl Lewis x determinant and has L-selectin ligand activityThe interaction of lubricin/proteoglycan 4 (PRG4) with toll-like receptors 2 and 4: an anti-inflammatory role of PRG4 in synovial fluid.Excess BMP Signaling in Heterotopic Cartilage Forming in Prg4-null TMJ Discs.Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.Galectin-3 Binds to Lubricin and Reinforces the Lubricating Boundary Layer of Articular Cartilage.Transcription, translation, and function of lubricin, a boundary lubricant, at the ocular surface.Mechanical motion promotes expression of Prg4 in articular cartilage via multiple CREB-dependent, fluid flow shear stress-induced signaling pathways.Lubricin: a novel potential biotherapeutic approaches for the treatment of osteoarthritis.Cell-based meniscal tissue engineering: a case for synoviocytes.
P2860
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P2860
The molecular structure and lubricating activity of lubricin isolated from bovine and human synovial fluids.
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年論文
@yue
1985年論文
@zh-hant
1985年論文
@zh-hk
1985年論文
@zh-mo
1985年論文
@zh-tw
1985年论文
@wuu
1985年论文
@zh
1985年论文
@zh-cn
name
The molecular structure and lu ...... ine and human synovial fluids.
@en
type
label
The molecular structure and lu ...... ine and human synovial fluids.
@en
prefLabel
The molecular structure and lu ...... ine and human synovial fluids.
@en
P2093
P2860
P356
P1433
P1476
The molecular structure and lu ...... ine and human synovial fluids.
@en
P2093
P2860
P304
P356
10.1042/BJ2250195
P407
P577
1985-01-01T00:00:00Z