Transmembrane domain interactions control biological functions of neuropilin-1
about
Receptor complexes for each of the Class 3 SemaphorinsGuidance molecules in lung cancerNRP1 function and targeting in neurovascular development and eye diseaseRole of Neuropilin-1 in Diabetic NephropathyNeuropilins and liverControl of cellular motility by neuropilin-mediated physical interactionsNeuropilins lock secreted semaphorins onto plexins in a ternary signaling complexVEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration, complex formation between NRP1 and VEGFR2, and signaling via FAK Tyr407 phosphorylationTransmembrane recognition of the semaphorin co-receptors neuropilin 1 and plexin A1: coarse-grained simulationsNeuropilin-1 in transplantation tolerance.Inhibition of tumor cell migration by LD22-4, an N-terminal fragment of 24-kDa FGF2, is mediated by Neuropilin 1Semaphorins and their receptors in lung cancer.Drugging Membrane Protein Interactions.Current drug design to target the Semaphorin/Neuropilin/Plexin complexes.Inhibition of PlexA1-mediated brain tumor growth and tumor-associated angiogenesis using a transmembrane domain targeting peptide.Inhibition of primary breast tumor growth and metastasis using a neuropilin-1 transmembrane domain interfering peptide.T-cell antigen receptor (TCR) transmembrane peptides: A new paradigm for the treatment of autoimmune diseases.Single-spanning transmembrane domains in cell growth and cell-cell interactions: More than meets the eye?Plexin structures are coming: opportunities for multilevel investigations of semaphorin guidance receptors, their cell signaling mechanisms, and functions.Neuropilins are multifunctional coreceptors involved in tumor initiation, growth, metastasis and immunity.Function of members of the neuropilin family as essential pleiotropic cell surface receptors.Neuropilin 1: function and therapeutic potential in cancer.The emerging role of class-3 semaphorins and their neuropilin receptors in oncology.Identification of a gene expression profile associated with the regulation of angiogenesis in endometrial cancer.A transmembrane domain and GxxxG motifs within L2 are essential for papillomavirus infection.Specific inhibition of a pathogenic receptor tyrosine kinase by its transmembrane domainCritical role of the platelet-derived growth factor receptor (PDGFR) beta transmembrane domain in the TEL-PDGFRbeta cytosolic oncoprotein.Peptide-based interference of the transmembrane domain of neuropilin-1 inhibits glioma growth in vivo.Neuropilin-1 mediates vascular permeability independently of vascular endothelial growth factor receptor-2 activation.Point mutations in dimerization motifs of the transmembrane domain stabilize active or inactive state of the EphA2 receptor tyrosine kinase.SOBIR1 requires the GxxxG dimerization motif in its transmembrane domain to form constitutive complexes with receptor-like proteins.De novo assembly and characterization of breast cancer transcriptomes identifies large numbers of novel fusion-gene transcripts of potential functional significanceIdentifying key juxtamembrane interactions in cell membranes using AraC-based transcriptional reporter assay (AraTM).Neuropilin-1 promotes Hedgehog signaling through a novel cytoplasmic motif.Cysteines in the neuropilin-2 MAM domain modulate receptor homooligomerization and signal transduction.VEGF-A121a binding to Neuropilins - A concept revisited.
P2860
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P2860
Transmembrane domain interactions control biological functions of neuropilin-1
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Transmembrane domain interactions control biological functions of neuropilin-1
@en
type
label
Transmembrane domain interactions control biological functions of neuropilin-1
@en
prefLabel
Transmembrane domain interactions control biological functions of neuropilin-1
@en
P2093
P2860
P356
P1476
Transmembrane domain interactions control biological functions of neuropilin-1
@en
P2093
Cécile Nasarre
Dominique Aunis
Gérard Crémel
Pierre Hubert
Sylvie Dirrig-Grosch
P2860
P304
P356
10.1091/MBC.E07-06-0625
P577
2007-11-28T00:00:00Z