Small molecule-mediated refolding and activation of myosin motor function.
about
Poorly understood aspects of striated muscle contractionTargeting the sarcomere to correct muscle functionStructure and function of cardiac troponin C (TNNC1): Implications for heart failure, cardiomyopathies, and troponin modulating drugsAn Automated Microscale Thermophoresis Screening Approach for Fragment-Based Lead DiscoveryThe novel cardiac myosin activator omecamtiv mecarbil increases the calcium sensitivity of force production in isolated cardiomyocytes and skeletal muscle fibres of the ratVarious Themes of Myosin Regulation.Structural basis for drug-induced allosteric changes to human β-cardiac myosin motor activityProbing the mechanism of cardiovascular drugs using a covalent levosimendan analog.MYBPC3 mutations are associated with a reduced super-relaxed state in patients with hypertrophic cardiomyopathy.Kinetic adaptation of human Myo19 for active mitochondrial transport to growing filopodia tipsThe Conserved Lysine-265 Allosterically Modulates Nucleotide- and Actin-binding Site Coupling in Myosin-2.Diatrack particle tracking software: review of applications and performance evaluation.Bringing dead proteins back to lifeThe role of super-relaxed myosin in skeletal and cardiac muscleA small-molecule modulator of cardiac myosin acts on multiple stages of the myosin chemomechanical cycle.Omecamtiv mercabil and blebbistatin modulate cardiac contractility by perturbing the regulatory state of the myosin filament.Allosteric modulation of cardiac myosin dynamics by omecamtiv mecarbil.Three mammalian tropomyosin isoforms have different regulatory effects on nonmuscle myosin-2B and filamentous β-actin in vitro.Unfolding of the myosin head by purealin in glycerol.
P2860
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P2860
Small molecule-mediated refolding and activation of myosin motor function.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Small molecule-mediated refolding and activation of myosin motor function.
@en
type
label
Small molecule-mediated refolding and activation of myosin motor function.
@en
prefLabel
Small molecule-mediated refolding and activation of myosin motor function.
@en
P2093
P2860
P50
P356
P1433
P1476
Small molecule-mediated refolding and activation of myosin motor function.
@en
P2093
Britta Stapel
Denise Hilfiker-Kleiner
Michael B Radke
P2860
P304
P356
10.7554/ELIFE.01603
P407
P577
2014-02-11T00:00:00Z